Alcohol
Volume 24, Issue 2 , Pages 111-115 , June 2001

Relapse prevention in alcoholics by cigarette smoking? Involvement of nicotinic–dopaminergic mechanisms

  • Lutz G. Schmidt

      Affiliations

    • Department of Psychiatry, University of Mainz, Untere Zahlbacher Straße 8, 55131 Mainz, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +49-6131-17-2920; fax: +49-6131-17-6690
    • ,
  • Michael Smolka

      Affiliations

    • Department of Psychiatry, Free University of Berlin, Eschenallee 3, 14050 Berlin, Germany

Received 21 August 2000 ,Revised 6 January 2001 ,Accepted 15 January 2001.

References 

  1. Abrams DB, Monti PM, Niaura RS, Rohsenow DJ, Colby SM. Interventions for alcoholics who smoke. Alcohol Health & Research World. 1996;20:111–117
  2. Batel P, Pessione F, Maitre C, Rueff B. Relationship between alcohol and tobacco dependencies among alcoholics who smoke. Addiction. 1995;90:977–980
  3. Blomqvist O, Engel JA, Nissbrandt H, Soderpalm B. The mesolimbic dopamine-activating properties of ethanol are antagonized by mecamylamine. Eur J Pharmacol. 1993;249:207–213
  4. Bobo JK, McIlvain HE, Lando HA, Walker RD, Leed-Kelly A. Effect of smoking cessation counseling on recovery from alcoholism: findings from a randomized community intervention trial. Addiction. 1998;93:877–887
  5. Dani JA, Heinemann S. Molecular and cellular aspects of nicotine abuse. Neuron. 1996;16:905–908
  6. Di Chiara G, Imperato A. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc Natl Acad Sci USA. 1988;85:5274–5278
  7. Dilling Hvon H, Mombour W, Schmidt MH. Klinisch-diagnostische Leitlinien. In: World Health Organization, Internationale Klassifikation Psychischer Störungen ICD–10. Bern Goettingen Toronto: Huber Verlag; 1993;
  8. Gessa GL, Muntoni F, Collu M, Vargiu L, Mereu G. Low doses of ethanol activate dopaminergic neurons in the ventral tegmental area. Brain Res. 1985;348:201–203
  9. National Institute on Alcohol Abuse and Alcoholism . Alcohol and tobacco. Alcohol Alert. 1998;39: http://www.niaaa.nih.govJanuary
  10. Pontieri FE, Tanda G, Orzi F, Di Chiara G. Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs. Nature. 1996;382:255–257
  11. Rohsenow DJ, Monti PM, Colby SM, Gulliver SB, Sirota AD, Niaura RS, et al. Effects of alcohol cues on smoking urges and topography among alcoholic men. Alcohol Clin Exp Res. 1997;21:101–107
  12. Schmidt LG, Dettling M, Graef KJ, Heinz A, Kuhn S, Podschus J, et al. Reduced dopaminergic function in alcoholics is related to severe dependence. Biol Psychiatry. 1996;39:193–198
  13. Schmidt LG, Kuhn S, Rommelspacher H. Pharmacological effects of lisuride shorten, expectations to receive the drug prolong the latency of relapse in weaned alcoholics. Eur Neuropsychopharmacol. 1997;7(Suppl 2):S259
  14. Schmidt LG, Schmidt K, Dufeu P, Ohse A, Rommelspacher H, Müller C. Superiority of carbohydrate deficient transferrin to γ-glutamyltransferase in detecting relapse in alcoholism. Am J Psychiatry. 1997;154:75–80
  15. Sher KJ, Gotham HJ, Erickson DJ, Wood PK. A prospective, high-risk study of the relationship between tobacco dependence and alcohol use disorders. Alcohol Clin Exp Res. 1996;20:485–492
  16. Smolka M, Kuhn S, Rommelspacher H, Schmidt LG. Effect of smoking on dopaminergic sensitivity in alcohol dependent patients. Alcohol Clin Exp Res. 1998;22 Suppl:151A
  17. Toneatto A, Sobell LC, Sobell MB, Kozlowski LT. Effect of cigarette smoking on alcohol treatment outcome. J Subst Abuse. 1995;7:245–252

PII: S0741-8329(01)00129-X

Alcohol
Volume 24, Issue 2 , Pages 111-115 , June 2001

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