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Alcohol
Volume 24, Issue 2
, Pages 117-128
, June 2001
Oral drug self-administration: an overview of laboratory animal studies
References
-
.
Oral self-administration of methohexital in baboons.
Psychopharmacology (Berlin). 1983;79:120–125
-
.
Oral self-administration of triazolam, diazepam and ethanol in the baboon: drug reinforcement and benzodiazepine physical dependence.
Psychopharmacology (Berlin). 1992;108:301–312
-
Bell, S. M., Brosman, C. H., Lemaire, G. A., & Meisch, R. A. The failure of orally self-administered phencyclidine to function as a reinforcer in the Lewis rat. Technical Report from the Laboratories of the Substance Abuse Research Center, Mental Sciences Institute, Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, SARC-1991-01, November 1991.
- . Water deprivation–induced oral self-administration of cocaine in the Lewis rat: evidence for locomotor effects but not reinforcement. Pharmacol Biochem Behav. 1993;45:749–754
-
.
The failure of cocaine to serve as an orally self-administered reinforcer in Lewis rats.
Behav Pharmacol. 1995;6:366–374
- . Effects of acute and chronic doses of naltrexone on ethanol self-administration in rhesus monkeys. Alcohol Clin Exp Res. 1998;22:359–366
-
.
Reduction of drug self-administration by an alternative non-drug reinforcer in rhesus monkeys: magnitude and temporal effects.
Psychopharmacology (Berlin). 2000;147:418–425
- . Acquisition of drug self-administration: environmental and pharmacological interventions. Exp Clin Psychopharmacol. 2000;8:312–325
-
.
Acquisition of oral phencyclidine (PCP) self-administration in rhesus monkeys: effects of dose and an alternative non-drug reinforcer.
Psychopharmacology (Berlin). 1998;137:132–138
- . Feeding, drug abuse, and the sensitization of reward by metabolic need. Neurochem Res. 1996;21:1455–1467
-
.
Oral self-administration of phencyclidine analogs by rhesus monkeys: conditioned taste and visual reinforcers.
Psychopharmacology (Berlin). 1982;78:116–120
- . Oral self-administration of phencyclidine (PCP) and PCP analogs and tolerance to PCP's behavioral effects. NIDA Res Monogr. 1982;41:74–81
- . Rapid acquisition of oral phencyclidine self-administration in food-deprived and food-satiated rhesus monkeys: concurrent phencyclidine and water choice. Pharmacol Biochem Behav. 1982;17:341–346
- . Tolerance to the behavioral effects of orally self-administered phencyclidine. Drug Alcohol Depend. 1982;9:213–224
- . The effect of second-order schedule history on fixed-ratio performance maintained by orally-delivered phencyclidine in rhesus monkeys. Pharmacol Biochem Behav. 1984;20:779–787
- . Effects of pentobarbital and d-amphetamine on oral phencyclidine self-administration in rhesus monkeys. Pharmacol Biochem Behav. 1984;20:137–143
- . Concurrent phencyclidine and saccharin access: presentation of an alternative reinforcer reduces drug intake. J Exp Anal Behav. 1985;43:131–144
- . Performance maintained by orally delivered phencyclidine under second-order, tandem and fixed-interval schedules in food-satiated and food-deprived rhesus monkeys. J Pharmacol Exp Ther. 1985;232:351–359
- . Concurrent access to two concentrations of orally delivered phencyclidine: effects of feeding conditions. J Exp Anal Behav. 1987;47:347–362
- . A quantitative assessment of phencyclidine dependence produced by oral self-administration in rhesus monkeys. J Pharmacol Exp Ther. 1987;242:405–412
-
.
Self-administration of orally-delivered phencyclidine and ethanol under concurrent fixed-ratio schedules in rhesus monkeys.
Psychopharmacology (Berlin). 1987;93:1–7
- . Oral self-administration of N-allylnormetazocine (SKF-10,047) stereoisomers in rhesus monkeys: substitution during phencyclidine self-administration and withdrawal. Pharmacol Biochem Behav. 1988;30:493–500
- . The economic context of drug and non-drug reinforcers affects acquisition and maintenance of drug-reinforced behavior and withdrawal effects. Drug Alcohol Depend. 1993;33:201–210
-
.
Interactions between food and addiction.
In:
Niesink RJM, Jaspers RMA, Kornet LMW, van Ree JM editor. Drugs of Abuse and Addiction: Neurobehavioral Toxicology. Boca Raton, FL: CRC Press LLC; 1999;p. 286–311
-
.
Effects of food FR and food deprivation on disruptions in food-maintained performance of monkeys during phencyclidine withdrawal.
Psychopharmacology (Berlin). 1991;104:143–149
- . Modifying drug-reinforced behavior by altering the economic conditions of the drug and a nondrug reinforcer. J Exp Anal Behav. 1991;56:361–376
- . Buprenorphine's effects on self-administration of smoked cocaine base and orally delivered phencyclidine, ethanol and saccharin in rhesus monkeys. J Pharmacol Exp Ther. 1992;261:26–37
- . Phencyclidine (PCP) self-administration and withdrawal in rhesus monkeys: effects of buprenorphine and dizocilpine (MK-801) pretreatment. Pharmacol Biochem Behav. 1994;48:723–732
-
.
Reductions in ethanol, phencyclidine, and food-maintained behavior by naltrexone pretreatment in monkeys is enhanced by open economic conditions.
Psychopharmacology (Berlin). 2000;148:412–422
- . Behavioral dependence on caffeine and phencyclidine in rhesus monkeys: interactive effects. Pharmacol Biochem Behav. 1988;31:927–932
-
.
Etonitazene as a reinforcer: oral intake of etonitazene by rhesus monkeys.
Psychopharmacology (Berlin). 1978;59:225–229
-
.
Concurrent etonitazene and water intake in rats: role of taste, olfaction, and auditory stimuli.
Psychopharmacology (Berlin). 1979;64:1–7
- . Oral phencyclidine (PCP) self-administration in rhesus monkeys: effects of feeding conditions. J Pharmacol Exp Ther. 1980;214:339–346
-
.
Increased drug-reinforced behavior due to food deprivation.
In:
Thompson T, Dews PB, Barrett JE editor.
Advances in Behavioral Pharmacology. Vol. 4:Orlando, FL: Academic Press; 1984;p. 47–88
- . Income alters choice between drug and an alternative nondrug reinforcer in monkeys. Exp Clin Psychopharmacol. 1993;1:110–120
-
.
Concurrent self-administration of ethanol and an alternative nondrug reinforcer in monkeys: effects of income (session length) on demand for drug.
Psychopharmacology (Berlin). 1995;120:1–9
-
.
Acquisition of oral phencyclidine self-administration in rhesus monkeys: effect of sex.
Psychopharmacology (Berlin). 2000;149:401–408
-
.
The behavioral pharmacology of alcohol and other drugs: emerging issues.
In:
Galanter M editors.
Recent Developments in Alcoholism. Vol. 8:New York: Plenum Press; 1990;p. 5–46
- . Oral d-amphetamine and ketamine self-administration by rhesus monkeys: effects of food deprivation. J Pharmacol Exp Ther. 1983;227:28–34
-
.
Increased phencyclidine self-administration due to food deprivation: interaction with concentration and training conditions.
Psychopharmacology (Berlin). 1984;84:299–303
- . Self-administration of orally-delivered methohexital in rhesus monkeys with phencyclidine or pentobarbital histories: effects of food deprivation and satiation. Pharmacol Biochem Behav. 1984;20:145–151
-
.
Multiple drug use in drug and alcohol addiction.
In:
Miller NS editors. Comprehensive Handbook of Drug and Alcohol Addiction. New York: Marcel Dekker; 1991;p. 87–113
- . Orally delivered pentobarbital as a reinforcer for rhesus monkeys with concurrent access to water: effects of concentration, fixed-ratio size, and liquid positions. Pharmacol Biochem Behav. 1982;16:113–117
-
.
Studies of the oral self-administration of pentobarbital by rhesus monkeys with concurrent access to water.
In:
Saito S, Yanagita T editor. Learning and Memory: Drugs as Reinforcer. Amsterdam: Excerpta Medica; 1982;p. 303–320
- . Oral ethanol reinforced behavior in inbred mice. Pharmacol Biochem Behav. 1986;24:1417–1421
-
.
Opioid operant self-administration, analgesia, stimulation and respiratory depression in μ-deficient mice.
Psychopharmacology (Berlin). 1995;117:23–31
- . Production of polydipsia in normal rats by an intermittent food schedule. Science. 1961;133:195–196
- . Food and amphetamine self-administration by baboons: effects of alternatives. J Exp Anal Behav. 1997;68:47–66
- . Ethanol and food pellet self-administration by baboons. Alcohol. 1998;16:183–188
- . Food and cocaine self-administration by baboons: effects of alternatives. J Exp Anal Behav. 1999;72:215–234
-
.
A novel protocol for studying food or drug seeking in rhesus monkeys.
Psychopharmacology (Berlin). 1997;132:209–216
- . The effects of d-amphetamine on intake of food and a sweet fluid containing cocaine. Pharmacol Biochem Behav. 1999;62:457–464
- . Orally delivered cocaine functions as a positive reinforcer in C57BL/6J mice. Pharmacol Biochem Behav. 1991;38:897–903
- . Oral ethanol self-administration in free-feeding rhesus monkeys. Alcohol Clin Exp Res. 1988;12:780–784
- . Establishment and maintenance of oral ethanol self-administration in the baboon. Drug Alcohol Depend. 1981;7:113–124
- . Drinking device for rhesus monkeys. Pharmacol Biochem Behav. 1976;4:609–610
- . Ethanol as a positive reinforcer via the oral route for rhesus monkeys: maintenance of fixed-ratio responding. Pharmacol Biochem Behav. 1976;4:473–475
-
.
Ethanol drinking by rhesus monkeys as a function of concentration.
Psychopharmacology (Berlin). 1978;57:133–136
- . Ethanol drinking by rhesus monkeys with concurrent access to water. Pharmacol Biochem Behav. 1979;10:777–782
- . Ethanol and water drinking by rhesus monkeys. J Stud Alcohol. 1981;42:192–201
-
.
Ethological contributions.
In:
Hersen M, Ammerman RT, Sisson LA editor. Handbook of Aggressive and Destructive Behavior in Psychiatric Patients. New York: Plenum Press; 1994;p. 17–32
- . Behavioral economics of drug self-administration: an introduction. Drug Alcohol Depend. 1993;33:165–172
- . Concurrent performances: reinforcement by different doses of intravenous cocaine in rhesus monkeys. J Exp Anal Behav. 1974;22:179–196
- . A choice procedure for drug reinforcers: cocaine and methylphenidate in the rhesus monkey. J Pharmacol Exp Ther. 1975;193:676–688
-
.
Drugs as reinforcers: pharmacological and behavioural factors.
In:
Liebman JM, Cooper SJ editor. The Neuropharmacological Basis of Reward. Oxford, United Kingdom: Oxford University Press; 1989;p. 164–213
-
.
Effects of triazolam on drinking in baboons with and without an oral self-administration history: a reinstatement phenomenon.
Psychopharmacology (Berlin). 1995;122:108–114
- . The effects of food deprivation and satiation on oral pentobarbital self-administration in rhesus monkeys. Pharmacol Biochem Behav. 1982;16:579–584
- . Oral pentobarbital intake in rhesus monkeys: effects of drug concentration under conditions of food deprivation and satiation. Pharmacol Biochem Behav. 1989;32:347–354
-
.
Animal models of craving for ethanol.
Addiction. 2000;95(Suppl 2):S73–S81
- . Pentobarbital self-administration in rhesus monkeys: drug concentration and fixed-ratio size interactions. J Exp Anal Behav. 1984;42:37–49
- . Oral drug self-administration in rhesus monkeys: interactions between drug amount and fixed-ratio size. J Exp Anal Behav. 1985;44:377–389
-
.
Relative reinforcing effects of pentobarbital solutions orally self-administered by rhesus monkeys under fixed-ratio and signaled DRL schedules.
Psychol Rec. 1991;41:551–583
-
.
Concurrent pentobarbital- and saccharin-maintained responding: effects of saccharin concentration and schedule conditions.
Psychopharmacology (Berlin). 1993;112:204–210
- . Ethanol-reinforced responding of naive rhesus monkeys: acquisition without induction procedures. Alcohol. 1992;9:547–554
- . Oral cocaine self-administration in rhesus monkeys: strategies for engendering reinforcing effects. Exp Clin Psychopharmacol. 1995;3:129–139
- . Ratio size and cocaine concentration effects on oral cocaine-reinforced behavior. J Exp Anal Behav. 1998;70:185–201
- . Cocaine self-administration under conditions of restricted and unrestricted food access. Exp Clin Psychopharmacol. 1999;7:324–337
-
Meisch, R. A. (1969a). Increased rate of ethanol self-administration as a function of experience. Reports from the Research Laboratories, Department of Psychiatry, University of Minnesota, No. PR-69-3.
-
.
Self-administration of pentobarbital by means of schedule-induced polydipsia.
Psychon Sci. 1969;16:16–17
- . The function of schedule-induced polydipsia in establishing ethanol as a positive reinforcer. Pharmacol Rev. 1975;27:465–473
-
.
Ethanol self-administration: infrahuman studies.
In:
Thompson T, Dews PB editor.
Advances in Behavioral Pharmacology. Vol. 1:New York: Academic Press; 1977;p. 35–84
-
.
Ethanol as a reinforcer for rats, monkeys and humans.
In:
Eriksson K, Sinclair JD, Kiianmaa K editor. Animal Models in Alcohol Research. London: Academic Press; 1980;p. 153–158
-
.
Alcohol self-administration by experimental animals.
In:
Smart RG, Cappell HD, Glaser FB, Israel Y, Kalant H, Popham RE, Schmidt W, Sellers EM editor.
Research Advances in Alcohol and Drug Problems. Vol. 8:New York: Plenum Press; 1984;p. 23–45
- . Oral self-administration of etonitazene in rhesus monkeys: use of a fading procedure to establish etonitazene as a reinforcer. Pharmacol Biochem Behav. 1995;50:571–580
- . Relative persistence of behavior: a fundamental measure of relative reinforcing effects. Exp Clin Psychopharmacol. 2000;8:333–349
- . Relative persistence of behavior: a reply to comments. Exp Clin Psychopharmacol. 2000;8:362–365
- . Orally self-administered cocaine in rhesus monkeys: transition from negative or neutral behavioral effects to positive reinforcing effects. Drug Alcohol Depend. 1993;32:143–158
- . Establishment of orally delivered drugs as reinforcers for rhesus monkeys: some relations to human drug dependence. NIDA Res Monogr. 1981;37:197–209
-
.
Oral drug self-administration: drugs as reinforcers.
In:
Bozarth MA editors. Methods of Assessing the Reinforcing Properties of Abused Drugs. New York: Springer-Verlag; 1987;p. 143–160
- . Orally delivered cocaine as a reinforcer for rhesus monkeys. Pharmacol Biochem Behav. 1990;35:245–249
- . Drinking of ethanol by rhesus monkeys: experimental strategies for establishing ethanol as a reinforcer. Adv Exp Med Biol. 1977;85B:443–463
- . Establishment of ethanol as a reinforcer for rhesus monkeys via the oral route: initial results. Adv Exp Med Biol. 1975;59:323–342
- . Pentobarbital drinking by rhesus monkeys: establishment and maintenance of pentobarbital-reinforced behavior. J Pharmacol Exp Ther. 1981;217:114–120
- . Oral self-administration of pentobarbital by rhesus monkeys: relative reinforcing effects under concurrent fixed-ratio schedules. J Exp Anal Behav. 1988;50:75–86
- . Oral self-administration of pentobarbital by rhesus monkeys: maintenance of behavior by different concurrently available volumes of drug solution. J Exp Anal Behav. 1989;52:111–126
- . Reinforcing effects of a pentobarbital–ethanol combination relative to each drug alone. Pharmacol Biochem Behav. 1990;35:443–450
- . Effects of feeding condition on orally delivered ethanol as a reinforcer for rhesus monkeys. Alcohol. 1991;8:55–63
-
.
Drug self-administration.
In:
van Haaren F editors. Methods in Behavioral Pharmacology. Amsterdam: Elsevier; 1993;p. 257–300
- . Oral self-administration of pentobarbital by rhesus monkeys: relative reinforcing effects under concurrent signalled differential-reinforcement-of-low-rates schedules. Drug Alcohol Depend. 1992;30:215–225
- . Matching under nonindependent variable-ratio schedules of drug reinforcement. J Exp Anal Behav. 1998;70:23–34
- . Establishment of etonitazene as a reinforcer for rats by use of schedule-induced drinking. Pharmacol Biochem Behav. 1977;7:195–203
-
.
Ethanol as a reinforcer: a review of laboratory studies with nonhuman primates.
Behav Pharmacol. 1994;5:425–440
- . Relative reinforcing effects of different doses of orally delivered cocaine. Drug Alcohol Depend. 1995;37:141–147
-
.
Animal research: drug self-administration.
In:
Niesink RJM, Jaspers RMA, Kornet LMW, van Ree JM editor. Drugs of Abuse and Addiction: Neurobehavioral Toxicology. Boca Raton, FL: CRC Press LLC; 1999;p. 64–97
-
.
Studies of oral reinforcement by benzodiazepines in rhesus monkeys.
NIDA Res Monogr. 1996;162:243
- . Orally delivered methadone as a reinforcer for rhesus monkeys: the relationship between drug concentration and choice. Pharmacol Biochem Behav. 1996;54:547–554
- . Ethanol intake in the absence of concurrent food reinforcement. Psychopharmacologia. 1971;22:72–79
- . Ethanol intake during schedule-induced polydipsia. Physiol Behav. 1972;8:471–475
- . Ethanol as a reinforcer: effects of fixed-ratio size and food deprivation. Psychopharmacologia. 1973;28:171–183
-
.
Ethanol as a reinforcer: an operant analysis of ethanol dependence.
In:
Singh JM, Lal H editor. Drug Addiction, Vol. 3: Neurobiology and Influences on Behavior. Miami: Symposia Specialists (Stratton Intercontinental Medical Book Corporation); 1974;p. 117–133
-
Meisch, R. A., Wahlstrom, R. J., & Pickens, R. W. (1970). Effects of substituting ethanol solutions for water during schedule induced polydipsia: initial results. Reports from the Research Laboratories, Department of Psychiatry, University of Minnesota, No. PR-70-1.
- . Operant performance by rats for alcohol reinforcement: a comparison of alcohol-preferring and nonpreferring animals. Q J Stud Alcohol. 1964;25:226–234
-
.
Factors affecting alcohol consumption in primates.
Psychosom Med. 1966;28:529–550
- . Preference factors in experimental alcoholism. Science. 1961;134:469–470
- . Food restriction and sex differences on concurrent, oral ethanol and water reinforcers in juvenile rhesus monkeys. Alcohol. 1999;17:35–40
- . Combined effects of buprenorphine and an alternative nondrug reinforcer on phencyclidine self-administration in rhesus monkeys. Exp Clin Psychopharmacol. 1996;4:68–76
-
.
Naltrexone pretreatment decreases the reinforcing effectiveness of ethanol and saccharin but not PCP or food under concurrent progressive-ratio schedules in rhesus monkeys.
Psychopharmacology (Berlin). 1999;141:436–446
-
.
Progressive ratio and behavioral economic evaluation of the reinforcing efficacy of orally delivered phencyclidine and ethanol in monkeys: effects of feeding conditions.
Psychopharmacology (Berlin). 1996;128:265–273
-
.
A comparison of progressive ratio schedules versus behavioral economic measures: effect of an alternative reinforcer on the reinforcing efficacy of phencyclidine.
Psychopharmacology (Berlin). 1997;132:95–103
-
.
Concurrent progressive-ratio schedules to compare reinforcing effectiveness of different phencyclidine (PCP) concentrations in rhesus monkeys.
Psychopharmacology (Berlin). 1999;144:163–174
- . Feeding conditions alter the demand for phencyclidine and ethanol: a behavioral economic analysis. Exp Clin Psychopharmacol. 1996;4:61–67
-
.
The microstructure of ethanol drinking: genetic and behavioral factors in the control of drinking patterns.
Addiction. 2000;95(Suppl 2):S61–S72
-
.
Neurobehavioral regulation of ethanol intake.
In:
Deitrich RA, Erwin VG editor. Pharmacological Effects of Ethanol on the Nervous System. Boca Raton, FL: CRC Press; 1996;p. 203–226
- . Effect of stress on oral fentanyl consumption in rats in an operant self-administration paradigm. Pharmacol Biochem Behav. 1993;46:315–322
- . Reinforcing effects of a combination of ethanol and methadone relative to each drug alone. Pharmacol Biochem Behav. 1998;61:367–374
-
.
Human methadone self-administration: effects of dose and ratio requirement.
Behav Pharmacol. 1996;7:130–137
- . Human ethanol self-administration. I: The interaction between response requirement and ethanol dose. Behav Pharmacol. 1997;8:91–100
- . Ethanol as an oral reinforcer in normal weight rhesus monkeys: dose-response functions. Alcohol. 1996;13:341–346
-
.
Orally delivered methadone as a reinforcer in rhesus monkeys.
Psychopharmacology (Berlin). 1996;123:111–118
- . Establishing benzodiazepines as oral reinforcers: midazolam and diazepam self-administration in rhesus monkeys. J Pharmacol Exp Ther. 1994;271:200–211
- . Oral ethanol self-administration in rhesus monkeys: behavioral and neurochemical correlates. Alcohol Clin Exp Res. 1999;23:1352–1361
-
.
Oral self-administration of ethanol, phencyclidine, methadone, pentobarbital and quinine in rhesus monkeys.
Psychopharmacology (Berlin). 1999;147:113–124
-
Wang, N.-S., Brown, V., Grabowski, J., & Meisch, R. A. (In press). Reinforcement by orally delivered methadone, cocaine, and methadone–cocaine combinations in rhesus monkeys: are the combinations better reinforcers? Psychopharmacology (Berlin).
- . Orally delivered methadone as a reinforcer: effects of the opioid antagonist naloxone. Drug Alcohol Depend. 1999;55:79–84
-
.
Quadazocine decreases responding reinforced by ethanol, sucrose, and phencyclidine fluid deliveries in rhesus monkeys: comparison to naltrexone's effects.
Psychopharmacology (Berlin). 1999;144:316–322
-
.
Naltrexone reduces ethanol- and sucrose-reinforced responding in rhesus monkeys.
Psychopharmacology (Berlin). 1998;139:53–61
- . Oral ethanol-reinforced responding in rhesus monkeys: effects of opioid antagonists selective for the μ-, κ-, or δ-receptor. Alcohol Clin Exp Res. 1998;22:1634–1639
- . Naltrexone reduces ethanol- and/or water-reinforced responding in rhesus monkeys: effect depends upon ethanol concentration. Alcohol Clin Exp Res. 1999;23:1462–1467
- . A behavioral economic analysis of concurrent ethanol- and water-reinforced responding in different preference conditions. Alcohol Clin Exp Res. 2000;24:980–986
PII: S0741-8329(01)00149-5
© 2001 Elsevier Science Inc. All rights reserved.
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Alcohol
Volume 24, Issue 2
, Pages 117-128
, June 2001
