Alcohol
Volume 24, Issue 3 , Pages 189-195 , July 2001

Chronic ethanol exposure enhances activating protein-1 transcriptional activity in human neuroblastoma cells

  • Ulrik Fried

      Affiliations

    • Department of Medical Neurochemistry, Institute of Laboratory Medicine, Lund University Hospital, 221 85 Lund, Sweden
    • Corresponding Author InformationCorresponding author. Tel.: +46-46-175375; fax: +46-46-149870
    • ,
  • Knut Kotarsky

      Affiliations

    • Department of Physiological Sciences, Division of Molecular Neurobiology, Lund University, 223 62 Lund, Sweden
    • ,
  • Christer Alling

      Affiliations

    • Department of Medical Neurochemistry, Institute of Laboratory Medicine, Lund University Hospital, 221 85 Lund, Sweden

Received 2 October 2000 ,Revised 22 December 2000 ,Accepted 27 February 2001.

References 

  1. Angel P, Imagawa M, Chiu R, Stein B, Imbra RJ, Rahmsdorf HJ, et al. Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell. 1987;49:729–739
  2. Angel P, Karin M. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim Biophys Acta. 1991;1072:129–157
  3. Asai K, Ishii A, Yao L, Diamond I, Gordon AS. Varying effects of ethanol on transfected cell lines. Alcohol Clin Exp Res. 1998;22:163–166
  4. Beckmann AM, Matsumoto I, Wilce PA. AP-1 and Egr DNA-binding activities are increased in rat brain during ethanol withdrawal. J Neurochem. 1997;69:306–314
  5. Cebers G, Hou Y-N, Cebere A, Terenius L, Liljequist S. Chronic ethanol enhances NMDA-induced AP-1 activity in cultured rat cerebellar granule cells. Neuroreport. 1996;8:217–220
  6. Chang SL, Patel NA, Romero AA. Activation and desensitization of Fos immunoreactivity in the rat brain following ethanol administration. Brain Res. 1995;679:89–98
  7. Diamond I, Gordon AS. Cellular and molecular neuroscience of alcoholism. Physiol Rev. 1997;77:1–20
  8. Ding W-Q, Fried U, Larsson C, Alling C. Ethanol exposure potentiates fosB and junB expression induced by muscarinic receptor stimulation in neuroblastoma SH-SY5Y cells. Alcohol Clin Exp Res. 1998;22:225–230
  9. Ding W-Q, Fried U, Larsson C, Alling C. Acute ethanol exposure attenuates expression of junD in human neuroblastoma cells. Neurochem Int. 1999;33:525–530
  10. Ding W-Q, Larsson C, Alling C. Ethanol exposure increases expression of c-jun and junD in human neuroblastoma cells. Neuroreport. 1996;7:2191–2195
  11. Gordon AS, Yao L, Wu ZL, Coe IR, Diamond I. Ethanol alters the subcellular localization of delta- and epsilon protein kinase C in NG108-15 cells. Mol Pharmacol. 1997;52:554–559
  12. Herdegen T, Leah JD. Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins. Brain Res Brain Res Rev. 1998;28:370–490
  13. Hou Y-N, Cebers G, Cebere A, Terenius L, Liljequist S. N-Methyl-d-aspartate-induced enhancement of activator protein-1 DNA binding activity is blocked by ethanol in cerebellar granule cells. Eur J Pharmacol. 1996;309:307–310
  14. Hughes P, Dragunow M. Induction of immediate-early genes and the control of neurotransmitter-regulated gene expression within the nervous system. Pharmacol Rev. 1995;47:133–178
  15. Karin M. The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem. 1995;270:16483–16486
  16. Morgan PF, Nadi NS, Karanian J, Linnoila M. Mapping rat brain structures activated during ethanol withdrawal: role of glutamate and NMDA receptors. Eur J Pharmacol. 1992;225:217–223
  17. Putzke J, Spanagel R, Tolle TR, Zieglgansberger W. The anti-craving drug acamprosate reduces c-fos expression in rats undergoing ethanol withdrawal. Eur J Pharmacol. 1996;317:39–48
  18. Reddy MA, Shukla SD. Potentiation of mitogen-activated protein kinase by ethanol in embryonic liver cells. Biochem Pharmacol. 1996;51:661–668
  19. Roivainen R, Hundle B, Messing RO. Protein kinase C and adaptation to ethanol. EXS. 1994;71:29–38
  20. Roivainen R, Hundle B, Messing RO. Ethanol enhances growth factor activation of mitogen-activated protein kinases by a protein kinase C–dependent mechanism. Proc Natl Acad Sci USA. 1995;92:1891–1895
  21. Ryabinin AE, Wang YM. Repeated alcohol administration differentially affects c-Fos and FosB protein immunoreactivity in DBA/2J mice. Alcohol Clin Exp Res. 1998;22:1646–1654
  22. Thiele TE, Roitman MF, Bernstein IL. c-Fos induction in rat brainstem in response to ethanol- and lithium chloride–induced conditioned taste aversions. Alcohol Clin Exp Res. 1996;20:1023–1028
  23. Zoeller RT, Fletcher DL. A single administration of ethanol simultaneously increases c-fos mRNA and reduces c-jun mRNA in the hypothalamus and hippocampus. Brain Res Mol Brain Res. 1994;24:185–191

PII: S0741-8329(01)00151-3

doi: 10.1016/S0741-8329(01)00151-3

Alcohol
Volume 24, Issue 3 , Pages 189-195 , July 2001

Article Tools

* Image Usage & Resolution