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Alcohol
Volume 25, Issue 2
, Pages 77-81
, October 2001
Chronic ethanol consumption increases homocysteine accumulation in hepatocytes
References
- . The influence of ethanol on hepatic transmethylation. Alcohol Alcohol. 1988;23:73–77
- . The effect of betaine in reversing alcoholic steatosis. Alcohol Clin Exp Res. 1997;21:1100–1102
- . Dietary betaine promotes generation of hepatic S-adenosylmethionine and protects the liver from ethanol-induced fatty infiltration. Alcohol Clin Exp Res. 1993;17:552–555
-
.
Ethanol feeding inhibits the activity of hepatic N5-methyltetrahydrofolate-homocysteine methyltransferase in the rat.
IRCS Med Sci. 1985;13:760–761
-
.
Adaptive increase in betaine-homocysteine methyltransferase activity maintains hepatic S-adenosylmethionine levels in ethanol-treated rats.
IRCS Med Sci. 1984;12:866–867
- . Three months supplementation of hyperhomocysteinaemic patients with folic acid and vitamin B6 improves biological markers of endothelial dysfunction. Br J Haematol. 1999;107:776–778
- . Endothelial dysfunction during acute methionine load in hyperhomocysteinaemic patients. Atherosclerosis. 1999;147:411–413
- . Modification of a HPLC method for assay of homocysteine in human plasma. J Chromatogr. 1993;617:136–139
- . Hyperhomocysteinemia in chronic alcoholism: relations to folic acid and vitamin B6 and B12 status. Nutrition. 2000;16:296–302
- . Regulation of the betaine content of rat liver. Arch Biochem Biophys. 1982;218:169–173
- . Hyperhomocysteinemia and the endocrine system: implications for atherosclerosis and thrombosis. Endocr Rev. 1999;20:738–759
- . Elevated plasma homocysteine in alcoholics. Alcohol Clin Exp Res. 1993;17:687–689
-
.
Guide for the Care and Use of Laboratory Animals. Washington, DC: National Academy Press; 1996;
- . Homocysteine and vitamins in cardiovascular disease. Clin Chem. 1998;44:1833–1843
- . Protein homocysteinylation: possible mechanism underlying pathological consequences of elevated homocysteine levels. FASEB J. 1999;13:2277–2283
-
.
Role of oxidant stress in endothelial dysfunction produced by experimental hyperhomocyst(e)inemia in humans.
Circulation. 1999;100:1161–1168
- . Liquid diet technique of ethanol administration: 1989 update. Alcohol Alcohol. 1989;24:197–211
- . Assessment of homocysteine status. J Inherit Metab Dis. 1997;20:286–294
- . Preparation of isolated rat liver cells. Methods Cell Biol. 1976;13:29–83
- . Homocysteine metabolism. Annu Rev Nutr. 1999;19:217–246
- . Effect of chronic alcohol consumption on total plasma homocysteine level in rats. Alcohol Clin Exp Res. 2000;24:259–264
- . Induction of TIMP-1 expression in rat hepatic stellate cells and hepatocytes: a new role for homocysteine in liver fibrosis. Biochim Biophys Acta. 1999;1455:12–22
PII: S0741-8329(01)00168-9
© 2001 Elsevier Science Inc. All rights reserved.
« Previous
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Alcohol
Volume 25, Issue 2
, Pages 77-81
, October 2001
