Alcohol
Volume 27, Issue 1 , Pages 43-46, May 2002

Alcoholic hepatitis:☆

inflammatory cell–mediated hepatocellular injury

  • Samuel W. French

      Affiliations

    • Corresponding Author InformationCorresponding author. Department of Pathology, Harbor-UCLA Medical Center, 1000 West Carson Street, Torrance, CA 90509, USA. Tel.: +1-310-222-2643; fax: +1-310-222-5333.(S.W. French)

Harbor-UCLA Medical Center, Torrance, CA 90509, USA

Received 23 November 2001; received in revised form 18 January 2002; accepted 3 February 2002.

Abstract 

The role that inflammatory cell injury plays in the pathogenesis of alcoholic liver disease is reviewed with emphasis on granulocytes and immunocytes. New insights regarding the mechanism of lymphocytic migration from the portal vein and lymphocytic-mediated hepatocellular injury are also reviewed.

Keywords:  Granulocytes, Lymphocytes, Immunologic synapse, Autoimmunity, CYP2E1, Protein adducts, Adhesion molecules

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☆ Editor: T.R. Jerrells

PII: S0741-8329(02)00205-7

Alcohol
Volume 27, Issue 1 , Pages 43-46, May 2002

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