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Alcohol
Volume 27, Issue 1
, Pages 47-52
, May 2002
Role of activated CD8+ T cells in the initiation and continuation of hepatic damage
References
- . Influence of chronic alcohol abuse on hepatitis C virus replication. Dig Dis. 2000;18:168–171
- . Assessment of liver histology in chronic alcoholics with and without hepatitis C virus infection. Dig Dis Sci. 2001;46:1393–1398
- . Mechanisms of class I restricted immunopathology. A transgenic mouse model of fulminant hepatitis. J Exp Med. 1993;178:1541–1554
- . Concerted action of the FasL/Fas and perforin/granzyme A and B pathways is mandatory for the development of early viral hepatitis but not for recovery from viral infection. J Virol. 2001;75:8781–8791
- . Activation and function of natural killer cell responses during viral infections. Curr Opin Immunol. 1997;9:24–34
- . HCV infection and chronic active hepatitis in alcoholics. Arch Virol Suppl. 1992;4:212–214
- . Pathogenesis of chronic hepatitis C (immunological features of hepatic injury and viral persistence). Hepatology. 1999;30:595–601
- . Immunopathology of hepatitis C. Springer Semin Immunopathol. 1997;19:57–68
- . Differential CD4+ and CD8+ T-cell responsiveness in hepatitis c virus infection. Hepatology. 2001;33:267–276
- . Cytotoxic T cells and viral hepatitis. J Clin Invest. 1997;99:1472–1477
- . Alcohol abuse, alcoholism, and damage to the immune system—a review. Alcohol Clin Exp Res. 1998;22:1927–1942
- . Cytoplasmic cytokines in the T cells of chronic alcoholics. (Letter). Alcohol Clin Exp Res. 2000;24:241–243
- . Independent and combined action of hepatitis C virus infection and alcohol consumption on the risk of symptomatic liver cirrhosis. Hepatology. 1998;27:914–919
- . Strange brew (T cells in the liver). Immunol Today. 1996;17:522–525
- . Modulation of caspase-3 activity and Fas ligand mRNA expression in rat liver cells in vivo by alcohol and lipopolysaccharide. Alcohol Clin Exp Res. 1999;23:349–356
- . Molecular basis for cytolytic T-lymphocyte recognition of the murine cytomegalovirus immediate-early protein pp89. J Virol. 1988;62:3965–3972
- . Ordered array of dendritic cells and CD8+ lymphocytes in portal infiltrates in chronic hepatitis C. Histopathology. 2001;39:373–381
- . Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage. J Exp Med. 1995;182:1223–1230
- . Recurrence of hepatitis C virus after loss of virus-specific CD4+ T-cell response in acute hepatitis C. Gastroenterology. 1999;117:933–941
- . Sustained dysfunction of antiviral CD8+ T lymphocytes after infection with hepatitis C virus. J Virol. 2001;75:5550–5558
- . Noncytolytic control of viral infections by the innate and adaptive immune response. Annu Rev Immunol. 2001;19:65–91
- . CD8+ T cells specific for a single nonamer epitope of Listeria monocytogenes are protective in vivo. J Exp Med. 1992;175:1531–1538
- . The role of alcoholism and liver disease in the appearance of serum antibodies against acetaldehyde adducts. Hepatology. 1988;8:569–574
- . The liver eliminates T cells undergoing antigen-triggered apoptosis in vivo. Immunity. 1994;1:741–749
- . Monoclonal and polyclonal antibodies against acetaldehyde-containing epitopes in acetaldehyde–protein adducts. Proc Natl Acad Sci U S A. 1986;83:7923–7927
-
.
Immunotoxic effects of ethanol.
In:
Dean JH, Luster MI, Munson AE, Kimber I editor. Immunotoxicology and Immunopharmacology. New York: Raven Press; 1994;p. 323–347
- . Murine model of ethanol-induced immunosuppression. Alcohol Clin Exp Res. 1990;14:546–550
- . Liver-derived DEC205+B220+CD19– dendritic cells regulate T cell responses. J Immunol. 2001;166:7042–7052
- . Naive and memory T lymphocytes migrate in comparable numbers through normal rat liver (activated T cells accumulate in the periportal field). J Immunol. 1999;163:4300–4307
- . Monocyte activation in alcoholic liver disease. Alcohol. 2002;27:53–61
- . Hepatocyte apoptosis is a pathologic feature of human alcoholic hepatitis. J Hepatol. 2001;34:248–253
- . Cytochrome P450 2E1-derived reactive oxygen species mediate paracrine stimulation of collagen I protein synthesis by hepatic stellate cells. J Biol Chem. 2002;277:9853–9864
- . Mechanisms for virus-induced liver disease (tumor necrosis factor–mediated pathology independent of natural killer and T cells during murine cytomegalovirus infection). J Virol. 1997;71:9248–9258
- . Ethanol (an enhancer of major histocompatibility complex antigen expression). FASEB J. 1987;1:469–473
- . Fas-mediated hepatocyte apoptosis is increased by hepatitis C virus infection and alcohol consumption, and may be associated with hepatic fibrosis (mechanisms of liver cell injury in chronic hepatitis C virus infection). J Viral Hepat. 2001;8:406–413
- . CD8-positive T lymphocytes specific for murine cytomegalovirus immediate-early antigens mediate protective immunity. J Virol. 1987;61:3102–3108
- . Hepatitis C and alcohol. Alcohol Clin Exp Res. 1999;23:1543–1551
- . Differential role of ethanol and acetaldehyde in the induction of oxidative stress in HEP G2 cells (effect on transcription factors AP-1 and NF-κB). Hepatology. 1999;30:1473–1480
- . Alcoholism is associated with hepatitis C but not hepatitis B in an urban population. Am J Gastroenterol. 1996;91:498–505
- . Liver damage preferentially results from CD8+ T cells triggered by high affinity peptide antigens. J Exp Med. 1998;188:1147–1157
- . Ethanol ingestion increases susceptibility of mice to Listeria monocytogenes. Alcohol Clin Exp Res. 1993;17:75–85
- . Early murine cytomegalovirus (MCMV) infection induces liver natural killer (NK) cell inflammation and protection through macrophage inflammatory protein 1α (MIP-1α)–dependent pathways. J Exp Med. 1998;187:1–14
- . The alcoholic patient with hepatitis C virus infection. Am J Med. 1999;107:95S–99S
- . Alcohol consumption by C57BL/6 mice is associated with depletion of lymphoid cells from the gut-associated lymphoid tissues and altered resistance to oral infections with Salmonella typhimurium. J Infect Dis. 2000;182:482–489
- . Alcohol consumption is associated with alterations in macrophage responses to interferon-γ and infection by Salmonella typhimurium. FEMS Immunol Med Microbiol. 2001;32:73–83
- . Ethanol (an enhancer of transplantation antigen expression). Alcohol Clin Exp Res. 1989;13:480–484
- . Initiation of alcoholic fatty liver and hepatic inflammation with a specific recall immune response in alcohol-consuming C57Bl/6 mice. Clin Exp Immunol. 2001;125:123–133
- . TH1 cytokine response of CD57+ T-cell subsets in healthy controls and patients with alcoholic liver disease. Alcohol. 2001;24:155–167
- . Relationship between alcoholic liver disease and HCV infection. Alcohol Alcohol Suppl. 1993;1A:77–84
- . Contribution of hepatitis C virus to the progression of alcoholic liver disease. Alcohol Clin Exp Res. 2000;24:112S–116S
- . Activating immunity in the liver. I. Liver dendritic cells (but not hepatocytes) are potent activators of IFN-γ release by liver NKT cells. J Immunol. 2001;167:1413–1422
- . Characterization of liver T-cell receptor γδ T cells obtained from individuals chronically infected with hepatitis C virus (HCV) (evidence for these T cells playing a role in the liver pathology associated with HCV infections). Hepatology. 2001;33:1312–1320
- . Strong CD8 T-cell responses following coimmunization with plasmids expressing the dominant pp89 and subdominant m84 antigens of murine cytomegalovirus correlate with long-term protection against subsequent viral challenge. J Virol. 2002;76:2100–2112
- . Essential role of tumor necrosis factor alpha in alcohol-induced liver injury in mice. Gastroenterology. 1999;117:942–952
☆ Editor: T.R. Jerrells
PII: S0741-8329(02)00210-0
© 2002 Elsevier Science Inc. All rights reserved.
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Alcohol
Volume 27, Issue 1
, Pages 47-52
, May 2002
