Alcohol
Volume 27, Issue 2 , Pages 107-114 , June 2002

Naltrexone modifies the palatability of basic tastes and alcohol in outbred male rats

Received 6 November 2000 ,Revised 1 March 2002 ,Accepted 9 March 2002.

References 

  1. Apfelbaum M, Mandenoff A. Naltrexone suppresses hyperphagia induced in the rat by a highly palatable diet. Pharmacol Biochem Behav. 1981;15:89–91
  2. Belknap JK, Crabbe JC, Young ER. Voluntary consumption of ethanol in 15 inbred mouse strains. Psychopharmacology (Berl). 1993;112:503–510
  3. Berridge KC, Grill HJ. Alternating ingestive and aversive consummatory responses suggest a two-dimensional analysis of palatability in rats. Behav Neurosci. 1983;97:563–573
  4. Brands B, Thornhill JA, Hirst M, Gowdey CW. Suppression of food intake and body weight gain by naloxone in rats. Life Sci. 1979;24:1773–1778
  5. Brown DR, Holtzman SG. Suppression of deprivation-induced food and water intake in rats and mice by naloxone. Pharmacol Biochem Behav. 1979;11:567–573
  6. Coonfield DL, Hill KG, Kaczmarek HJ, Ferraro FM, Schneider P, Chandler L, et al. Low doses of naltrexone alter alcohol palatability and consumption in rats. Alcohol Clin Exp Res. 2000;24:14A;[Abstract]
  7. Cooper SJ. Behaviourally-specific hyperdipsia in the non-deprived rat following acute morphine treatment. Neuropharmacology. 1981;20:469–471
  8. Cooper SJ, Gilbert DB. Naloxone suppresses fluid consumption in tests of choice between sodium chloride solutions and water in male and female water-deprived rats. Psychopharmacology (Berl). 1984;84:362–367
  9. Gosnell BA, Majchrzak MJ. Centrally administered opioid peptides stimulate saccharin intake in nondeprived rats. Pharmacol Biochem Behav. 1989;33:805–810
  10. Gosnell BA, Majchrzak MJ. Effects of a selective mu opioid receptor agonist and naloxone on the intake of sodium chloride solutions. Psychopharmacology (Berl). 1990;100:66–71
  11. Grill HJ. Introduction (physiological mechanisms in conditioned taste aversions). Ann NY Acad Sci. 1985;443:67–88
  12. Grill HJ, Berridge KC. Taste reactivity as a measure of the neural control of palatability. Prog Psychobiol Physiol Psychol. 1985;11:1–61
  13. Grill HJ, Norgren R. The taste reactivity test. I. Mimetic responses to gustatory stimuli in neurologically normal rats. Brain Res. 1978;143:263–279
  14. Hill KG, Kiefer SW. Naltrexone treatment increases the aversiveness of alcohol for outbred rats. Alcohol Clin Exp Res. 1997;21:637–641
  15. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council . Guide for the Care and Use of Laboratory Animals. Washington, DC: National Academy Press; 1996;
  16. Jalowiec JE, Panksepp J, Zolovick AJ, Najam N, Herman BH. Opioid modulation of ingestive behavior. Pharmacol Biochem Behav. 1981;15:477–484
  17. Kampov-Polevoy AB, Garbutt JC, Janowsky DS. Association between preference for sweets and excessive alcohol intake (a review of animal and human studies). Alcohol Alcohol. 1999;34:386–395
  18. Kampov-Polevoy AB, Kasheffskaya OP, Sinclair JD. Initial acceptance of ethanol (gustatory factors and patterns of alcohol drinking). Alcohol. 1990;7:83–85
  19. Parker LA, Maier S, Rennie M, Crebolder J. Morphine- and naltrexone-induced modification of palatability (analysis by the taste reactivity test). Behav Neurosci. 1992;106:999–1010
  20. Sanger DJ, McCarthy PS. Differential effects of morphine on food and water intake in food deprived and freely-feeding rats. Psychopharmacology (Berl). 1980;72:103–106
  21. Sanger DJ, McCarthy PS. Increased food and water intake produced in rats by opiate receptor agonists. Psychopharmacology (Berl). 1981;74:217–220
  22. Stapleton JM, Ostrowski NL, Merriman VJ, Lind MD, Reid LR. Naloxone reduces fluid consumption in water deprived and nondeprived rats. Bull Psychon Sci. 1979;13:237–239
  23. Volpicelli JR, Alterman AI, Hayashida M, O'Brien CP. Naltrexone in the treatment of alcohol dependence. Arch Gen Psychiatry. 1992;49:876–880
  24. Weldon DT, O'Hare E, Cleary J, Billington CJ, Levine AS. Effect of naloxone on intake of cornstarch, sucrose, and polycose diets in restricted and nonrestricted rats. Am J Physiol. 1996;270:R1183–R1188

☆ Editor: T.R. Jerrells

PII: S0741-8329(02)00220-3

Alcohol
Volume 27, Issue 2 , Pages 107-114 , June 2002

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