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Alcohol
Volume 31, Issue 1
, Pages 93-97
, August 2003
AA and ANA rats exhibit the R100Q mutation in the GABAA receptor α6 subunit
References
- . Genomic screen for QTLs underlying alcohol consumption in the P and NP rat lines. Mamm Genome. 1998;9:949–955
- . Withdrawal from chronic intermittent ethanol treatment changes subunit composition, reduces synaptic function, and decreases behavioral responses to positive allosteric modulators of GABAA receptors. Mol Pharmacol. 2003;63:53–64
- . Ethanol drinking behaviour in Sardinian alcohol-preferring rats. Alcohol Alcohol. 1997;32:443–453
- . Sardinian alcohol-preferring rats: a genetic animal model of anxiety. Physiol Behav. 1995;57:1181–1185
- . Genetic animal models of alcohol and drug abuse. Science. 1994;264:1715–1723
- . Hybridization of genomic DNA to oligonucleotide probes in the presence of tetramethylammonium chloride. Methods Enzymol. 1987;152:447–451
- . Ethyl alcohol consumption: valid measurement in albino rats. Science. 1968;161:76–77
- . Rat strains specially selected for their voluntary alcohol consumption. Ann Med Exp Biol Fenn. 1971;49:67–72
- . Effect of spontaneous ingestion of ethanol on brain dopamine metabolism. Life Sci. 1989;44:281–287
- . The role of GABAA receptors in the acute and chronic effects of ethanol. Psychopharmacology (Berl). 1998;139:2–19
- . Revitalization of the AA and ANA rat lines: effects on some line characteristics. Alcohol. 1984;1:71–75
- . Characterization of a cerebellar granule cell–specific gene encoding the γ-aminobutyric acid type A receptor α6 subunit. J Neurochem. 1996;67:907–916
- . Benzodiazepine-induced motor impairment linked to point mutation in cerebellar GABAA receptor. Nature. 1993;361:356–359
- . Selective breeding of alcohol preference and associated responses. Behav Genet. 1993;23:163–170
- . Molecular associations of alcohol-seeking behavior in rat lines selectively bred for high and low voluntary ethanol drinking. Alcohol Alcohol Suppl. 1991;1:121–124
-
.
New strains of rats with alcohol preference and nonpreference.
In:
Thurman RG, Williamson JR, Drott H, Chance B editor. Alcohol and Aldehyde Metabolizing Systems. New York: Academic Press; 1977;p. 537–544
- . Thirty-two years of selection of rats by ethanol preference: UChA and UChB strains. Neurobehav Toxicol Teratol. 1983;5:171–178
- . The R100Q mutation of the GABAA α6 receptor subunit may contribute to voluntary aversion to ethanol in the sNP rat line. Brain Res Mol Brain Res. 2001;87:263–270
- . Performance in the cross-maze and slip funnel tests of four pairs of rat lines selectively bred for divergent alcohol drinking behavior. Addict Biol. 1996;1:273–280
-
.
Oral ethanol reinforcement in the rat: effect of the partial inverse benzodiazepine agonist RO15-4513.
Pharmacol Biochem Behav. 1987;3:517–519
- . Characterization of wild-type (R100R) and mutated (Q100Q) GABAA α6 subunit in Sardinian alcohol non-preferring rats (sNP). Brain Res. 2003;967:98–105
- . Selective genotyping for the role of 5-HT2A, 5-HT2C, and GABA α6 receptors and the serotonin transporter in the level of response to alcohol: a pilot study. Biol Psychiatry. 1999;45:647–651
- . Association of GABAA receptors and alcohol dependence and the effects of genetic imprinting. Am J Med Genet. 2003;117B:39–45
PII: S0741-8329(03)00190-3
doi: 10.1016/j.alcohol.2003.07.003
© 2003 Elsevier Inc. All rights reserved.
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Alcohol
Volume 31, Issue 1
, Pages 93-97
, August 2003
