Alcohol
Volume 32, Issue 1 , Pages 9-18 , January 2004

Acute ethanol administration selectively impairs spatial memory in C57BL/6J mice

Received 4 November 2002 ,Revised 25 September 2003 ,Accepted 30 September 2003.

References 

  1. Best PJ, White AM. Hippocampal cellular activity: a brief history of space. Proc Natl Acad Sci U S A. 1998;95:2717–2719
  2. de Bruin JP, Swinkels WA, de Brabander JM. Response learning of rats in a Morris water maze: involvement of the medial prefrontal cortex. Behav Brain Res. 1997;85:47–55
  3. Givens BS, Breese GR. Site-specific enhancement of γ-aminobutyric acid–mediated inhibition of neural activity by ethanol in the rat medial septal area. J Pharmacol Exp Ther. 1990;254:528–538
  4. Inman-Wood SL, Williams MT, Morford LL, Vorhees CV. Effects of prenatal cocaine on Morris and Barnes maze tests of spatial learning and memory in the offspring of C57BL/6J mice. Neurotoxicol Teratol. 2000;22:547–557
  5. Jarrard LE. Selective hippocampal lesions and behavior: effects of kainic acid lesions on performance of place cells and cue tasks. Behav Neurosci. 1983;97:873–889
  6. Jarrard LE. On the use of ibotenic acid to lesion selectively different components of the hippocampal formation. J Neurosci Methods. 1989;29:251–259
  7. Jarrard LE. On the role of the hippocampus in learning and memory in the rat. Behav Neural Biol. 1993;60:9–26
  8. Lovinger DM, White G, Weight FF. Ethanol inhibits NMDA-activated ion current in hippocampal neurons. Science. 1989;243:1721–1724
  9. Matthews DB, Best PJ. Fimbria/fornix lesions facilitate the learning of a nonspatial task. Psychon Bull Rev. 1995;2:113–116
  10. Matthews DB, Ilgen M, White AM, Best PJ. Acute ethanol administration impairs spatial performance while facilitating nonspatial performance in rats. Neurobiol Learn Mem. 1999;72:169–179
  11. Matthews DB, Simson PE, Best PJ. Acute ethanol impairs spatial memory but not stimulus/response memory in the rat. Alcohol Clin Exp Res. 1995;19:902–909
  12. Matthews DB, Simson PE, Best PJ. Ethanol alters spatial processing of hippocampal place cells: a mechanism for impaired navigation when intoxicated. Alcohol Clin Exp Res. 1996;20:404–407
  13. Melia KR, Ryabinin AE, Corodimas KP, Wilson MC, Ledoux JE. Hippocampal-dependent learning and experience-dependent activation of the hippocampus are preferentially disrupted by ethanol. Neuroscience. 1996;74:313–322
  14. Miller V, Best PJ. Spatial correlates of hippocampal unit activity are altered by lesions of the fornix and endorhinal cortex. Brain Res. 1980;194:311–323
  15. Morris RGM, Garrud P, Rawlins JNP, O'Keefe J. Place navigation impaired in rats with hippocampal lesions. Nature. 1982;297:681–683
  16. Nadel L. The hippocampus and space revisited. Hippocampus. 1991;1:221–229
  17. O'Keefe J, Dostrovsky J. The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat. Brain Res. 1971;34:171–175
  18. O'Keefe J, Nadel L. The Hippocampus as a Cognitive Map. Oxford, England: Oxford University Press; 1978;
  19. Packard MG, Hirsh R, White NM. Differential effects of fornix and caudate nucleus lesions on two radial arm maze tasks: evidence for multiple memory systems. J Neurosci. 1989;9:1465–1472
  20. Ryabinin AE, Miller MN, Durrant S. Effects of acute alcohol administration on object recognition learning in C57BL/6J mice. Pharmacol Biochem Behav. 2002;71:307–312
  21. Simson PE, Criswell HE, Breese GR. Ethanol potentiates γ-aminobutyric acid–mediated inhibition in the inferior colliculus: evidence for local ethanol/γ-aminobutyric acid interactions. J Pharmacol Exp Ther. 1991;259:1288–1293
  22. Simson PE, Criswell HE, Breese GR. Inhibition of NMDA-evoked electrophysiological activity by ethanol in selected brain regions: evidence for ethanol-sensitive and ethanol-insensitive NMDA-evoked responses. Brain Res. 1993;607:9–16
  23. Tolman EC. Cognitive maps in rats and men. Psychol Rev. 1948;55:189–208
  24. VanDoren MJ, Matthews DB, Janis GC, Grobin AC, Devaud LL, Morrow AL. Neuroactive steroid 3α-hydroxy-5α-pregnan-20-one modulates electrophysiological and behavioral actions of ethanol. J Neurosci. 2000;20:1982–1989
  25. Whishaw IQ, Hines DJ, Wallace DG. Dead reckoning (path integration) requires the hippocampal formation: evidence from spontaneous exploration and spatial learning tasks in light (allothetic) and dark (idiothetic) tests. Behav Brain Res. 2001;127:49–69
  26. White AM, Best PJ. Effects of ethanol on hippocampal place-cell and interneuron activity. Brain Res. 2000;876:154–165
  27. White AM, Elek TM, Beltz TL, Best PJ. Spatial performance is more sensitive to ethanol than nonspatial performance regardless of cue proximity. Alcohol Clin Exp Res. 1998;22:2102–2107

PII: S0741-8329(03)00240-4

doi: 10.1016/j.alcohol.2003.09.005

Alcohol
Volume 32, Issue 1 , Pages 9-18 , January 2004