Alcohol
Volume 33, Issue 2 , Pages 127-138 , June 2004

Influence of vitamin E, sodium selenite, and astrocyte-conditioned medium on neuronal survival after chronic exposure to ethanol

Received 4 December 2003 ,Revised 1 June 2004 ,Accepted 12 June 2004.

References 

  1. Agar E, Bosnak M, Amanvermez R, Demir S, Ayyildiz M, Celik C. The effect of ethanol on lipid peroxidation and glutathione level in the brain stem of rat. Neuroreport. 1999;10:1799–1801
  2. An, G. J., Hong, Z. Y., & Quin, W. X. (1992). Effect of selenium selenite (ss) on action potential of isolated guinea pig papillary muscle and pig Purkinje fibers. Proceedings of the 5th Symposium on Selenium in Biology and Medicine, Nashville, Tennessee, July 20–23, p. 86.
  3. Banker GA. Trophic interactions between astroglial cells and hippocampal neurons in culture. Science. 1980;209:809–810
  4. Beisswenger TB, Holmquist B, Vallee BL. χ-ADH is the sole alcoholic dehydrogenase isoenzyme of mammalian brains: implications and inferences. Proc Natl Acad Sci U S A. 1985;82:8369–8373
  5. Bell H, Bjoerneboe A, Eidsvoll B, Norum KR, Raknerud N, Try K, et al. Reduced concentration of hepatic α-tocopherol in patients with alcoholic liver cirrhosis. Alcohol Alcohol. 1992;27:39–42
  6. Bondy SC, Guo SX, Adams JD. Prevention of ethanol-induced changes in reactive oxygen parameters by α-tocopherol. Alcohol Alcohol. 1996;31:403–410
  7. Booher J, Sensenbrenner M. Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures. Neurobiology. 1972;2:97–105
  8. Brown DR. Neurons depend on astrocytes in a coculture system for protection from glutamate toxicity. Mol Cell Neurosci. 1999;13:379–389
  9. Burton GW, Ingold KU. Vitamin E as an in vitro and in vivo antioxidant. Ann N Y Acad Sci. 1989;570:7–22
  10. Calabrese V, Renis M, Calderone A, Russo A, Reale S, Barcellona ML, et al. Stress proteins and SH-groups in oxidant-induced cellular injury after chronic ethanol administration in rat. Free Radic Biol Med. 1998;24:1159–1167
  11. Chen Y, Vartiainen NE, Ying W, Chan PH, Koistinaho J, Swanson RA. Astrocytes protect neurons from nitric oxide toxicity by a glutathione-dependent mechanism. J Neurochem. 2001;77:1601–1610
  12. Cohen G, Sinet PM, Heikkila R. Ethanol oxidation by rat brain in vivo. Alcohol Clin Exp Res. 1980;4:366–370
  13. Daval JL, De Vasconcelos AP, Lartaud I. Morphological and neurochemical effects of diazepam and phenobarbital on selective culture of neurons from fetal rat brain. J Neurochem. 1988;50:665–672
  14. Denizot F, Lang R. Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J Immunol Methods. 1986;89:271–277
  15. Desagher S, Glowinski J, Premont J. Astrocytes protect neurons from hydrogen peroxide toxicity. J Neurosci. 1996;16:2553–2562
  16. Dringen R, Gutterer JM, Hirrlinger J. Glutathione metabolism in brain. Metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species. Eur J Biochem. 2000;267:4912–4916
  17. Dringen R, Pfeiffer B, Hamprecht B. Synthesis of the antioxidant glutathione in neurons: supply by astrocytes of CysGly as precursor for neuronal glutathione. J Neurosci. 1999;19:562–569
  18. Drukarch B, Schepens E, Jongenelen CAM, Stoof JC, Langeveld CH. Astrocyte-mediated enhancement of neuronal survival is abolished by glutathione deficiency. Brain Res. 1997;770:123–130
  19. Ehrhart J, Zeevalk GD. Hydrogen peroxide removal and glutathione mixed disulfide formation during metabolic inhibition in mesencephalic cultures. J Neurochem. 2001;77:1496–1507
  20. Eysseric H, Gonthier B, Soubeyran A, Bessard G, Saxod R, Barret L. There is no simple method to maintain a constant ethanol concentration in long-term cell culture: keys to a solution applied to the survey of astrocytic ethanol absorption. Alcohol. 1997;14:111–115
  21. Gonthier B, Eysseric H, Soubeyran A, Daveloose D, Saxod R, Barret L. Free radical production after exposure of astrocytes and astrocytic C6 glioma cells to ethanol. Preliminary results. Free Radic Res. 1997;27:645–656
  22. Guerri C, Grisolia S. Changes in glutathione in acute and chronic alcohol intoxication. Pharmacol Biochem Behav. 1980;13(Suppl 1):53–61
  23. Haendeler J, Zeiher AM, Dimmeler S. Vitamin C and E prevent lipopolysaccharide-induced apoptosis in human endothelial cells by modulation of Bcl-2 and Bax. Eur J Pharmacol. 1996;317:407–411
  24. Hagen BF, Bjørneboe A, Bjørneboe G-EA, Drevon CA. Effect of chronic ethanol consumption on the content of α-tocopherol in subcellular fractions of rat liver. Alcohol Clin Exp Res. 1989;13:246–251
  25. Halliwell B. Antioxidants in human health and disease. Annu Rev Nutr. 1996;16:33–50
  26. Halliwell B, Gutteridge JMC. Free Radicals in Biology and Medicine. (3rd ed.). Oxford/New York: Oxford University Press; 1999;
  27. Heaton MB, Madorsky I, Paiva M, Mayer J. Influence of ethanol on neonatal cerebellum of BDNF gene-deleted animals: analyses of effects on Purkinje cells, apoptosis-related proteins, and endogenous antioxidants. J Neurobiol. 2002;51:160–176
  28. Heaton MB, Mitchell JJ, Paiva M. Amelioration of ethanol-induced neurotoxicity in the neonatal rat central nervous system by antioxidant therapy. Alcohol Clin Exp Res. 2000;24:512–518
  29. Heaton MB, Paiva M, Swanson DJ, Walker DW. Responsiveness of cultured septal and hippocampal neurons to ethanol and neurotrophic substances. J Neurosci Res. 1994;39:305–318
  30. Hertz L, Juurlink BHJ, Fosmark H, Schausboe A. Astrocytes in primary culture. In:  Pfeiffer SE editors. Neuroscience Approached Through Cell Culture. Boca Raton, FL: CRC Press; 1982;p. 175–186
  31. Hertz L, Juurlink HJ, Szuchet S. Cell cultures. In:  Lajtha A editors. Handbook of Neurochemistry. New York: Plenum Press; 1985;p. 603–661
  32. INSERM, expertise collective. (2001). Alcool — effets sur la santé (Editions Inserm). (Les éditions INSERM, 101 rue de Tolbiac, 75013 Paris, France. E-mail address for inquiries and ordering of cited book (358 pages): durrande@tolbiac.inserm.fr.)
  33. Kanbağli Ö, Balkan J, Aykaç-Toker G, Uysal M. Hepatic mitochondrial prooxidant and antioxidant status in ethanol-induced liver injury in rats. Biol Pharm Bull. 2002;25:1482–1484
  34. Lamarche F, Gonthier B, Signorini N, Eysseric H, Barret L. Acute exposure of cultured neurones to ethanol results in reversible DNA single-strand breaks; whereas chronic exposure causes loss of cell viability. Alcohol Alcohol. 2003;38:550–558
  35. Langeveld CH, Jongenelen CAM, Schepens E, Stoof JC, Bast A, Drukarch B. Cultured rat striatal and cortical astrocytes protect mesencephalic dopaminergic neurons against hydrogen peroxide toxicity independent of their effect on neuronal development. Neurosci Lett. 1995;192:13–16
  36. Lieber CS. Alcohol: its metabolism and interaction with nutrients. Annu Rev Nutr. 2000;20:395–430
  37. Lizard G, Miguet C, Besséde G, Monier S, Gueldry S, Neel D, et al. Impairment with various antioxidants of the loss of mitochondrial transmembrane potential and of the cytosolic release of cytochrome c occurring during 7-ketocholesterol-induced apoptosis. Free Radic Biol Med. 2000;28:743–753
  38. Lokhorst DK, Druse MJ. Effects of ethanol on cultured fetal astroglia. Alcohol Clin Exp Res. 1993;17:810–815
  39. Luo J, Miller MW. Transforming growth factor β1-regulated cell proliferation and expression of neural cell adhesion molecule in B104 neuroblastoma cells: differential effects of ethanol. J Neurochem. 1999;72:2286–2293
  40. Luo J, West JR, Pantazis NJ. Nerve growth factor and basic fibroblast growth factor protect rat cerebellar granule cells in culture against ethanol-induced cell death. Alcohol Clin Exp Res. 1997;21:1108–1120
  41. MacLennan AJ, Lee N, Walker DW. Chronic ethanol administration decreases brain-derived neurotrophic factor gene expression in the rat hippocampus. Neurosci Lett. 1995;197:105–108
  42. Makar TK, Nedergaard M, Preuss A, Gelbard AS, Perumal AS, Cooper AJL. Vitamin E, ascorbate, glutathione, glutathione disulfide, and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: evidence that astrocytes play an important role in antioxidative processes in the brain. J Neurochem. 1994;62:45–53
  43. Mansouri A, Demeilliers C, Amsellem S, Pessayre D, Fromenty B. Acute ethanol administration oxidatively damages and depletes mitochondrial DNA in mouse liver, brain, heart, and skeletal muscles: protective effects of antioxidants. J Pharmacol Exp Ther. 2001;298:737–743
  44. Mattson MP, Lovell MA, Furukawa K, Markesbery WR. Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons. J Neurochem. 1995;65:1740–1751
  45. Miller RR, Slathar JR, Luvisotto ML. α-tocopherol and γ-tocopherol attenuate ethanol-induced changes in membrane fatty acid composition in embryonic chick brains. Teratology. 2000;62:26–35
  46. Mitchell JJ, Paiva M, Heaton MB. The antioxidants vitamin E and β-carotene protect against ethanol-induced neurotoxicity in embryonic rat hippocampal cultures. Alcohol. 1999;17:163–168
  47. Nadiger H, Marcus SR, Chavdrakala MV. Lipid peroxidation and ethanol toxicity in rat brain: effect of vitamin E deficiency and supplementation. Med Sci Res. 1988;16:1273–1274
  48. Nakano T, Fujimoto T, Shimooki S, Fukudome T, Uchida T, Tsuji T, et al. Transient elevation of nerve growth factor content in the rat hippocampus and frontal cortex by chronic ethanol treatment. Psychiatry Clin Neurosci. 1996;50:157–160
  49. Nordmann R. Oxidative stress from alcohol in the brain. Alcohol Alcohol. 1987;(Suppl 1):75–82
  50. Nordmann R, Ribière C, Rouach H. Implication of free radical mechanism in ethanol-induced cellular injury. Free Radic Biol Med. 1992;12:219–240
  51. Pan Z, Perez-Polo R. Role of nerve growth factor in oxidant homeostasis: glutathione metabolism. J Neurochem. 1993;61:1713–1721
  52. Pantazis NJ, Zaheer A, Dai D, Zaheer S, Green SH, Lim R. Transfection of C6 glioma cells with glia maturation factor upregulates brain-derived neurotrophic factor and nerve growth factor: trophic effects and protection against ethanol toxicity in cerebellar granule cells. Brain Res. 2000;865:59–76
  53. Qu X, Huang K, Wu Z, Zhong S, Chen Z, Xu H. Purification of the newly found selenium-containing proteins in the arterial wall and brain of the rat. Biochem Biophys Res Commun. 2000;270:688–694
  54. Rashba-Step J, Turro NJ, Cederbaum AI. Increased NADPH- and NADH-dependent production of superoxide and hydroxyl radicals by microsomes after chronic ethanol treatment. Arch Biochem Biophys. 1993;300:401–408
  55. Rayman MP. The importance of selenium to human health. Lancet. 2000;356:233–241
  56. Ribière C, Hininger I, Saffar-Boccara C, Sabourault D, Nordmann R. Mitochondrial respiratory activity and superoxide radical generation in the liver, brain and heart after chronic ethanol intake. Biochem Pharmacol. 1994;47:1827–1833
  57. Rouach H, Houzé P, Gentil M, Orfanelli M-T, Nordmann R. Changes in some pro- and antioxidants in rat cerebellum after chronic alcohol intake. Biochem Pharmacol. 1997;53:539–545
  58. Rouach H, Houzé P, Orfanelli MT, Gentil M, Nordmann R. Effects of chronic ethanol intake on some anti- and pro-oxidants in rat cerebellum. Alcohol Alcohol. 1991;26:257;(Abstract)
  59. Sagara JI, Miura K, Bannai S. Maintenance of neuronal glutathione by glial cells. J Neurochem. 1993;61:1672–1676
  60. Sampath D, Jackson GR, Werrbach-Perez K, Perez-Polo JR. Effects of nerve growth factor on glutathione peroxidase and catalase in PC12 cells. J Neurochem. 1994;62:2476–2479
  61. Spallholz JE. Free radical generation by selenium compounds and their prooxidant toxicity. Biomed Environ Sci. 1997;10:260–270
  62. Stewart VC, Stone R, Gegg ME, Sharpe MA, Hurst RD, Clark JB, et al. Preservation of extracellular glutathione by an astrocyte derived factor with properties comparable to extracellular superoxide dismutase. J Neurochem. 2002;83:984–991
  63. Tanaka J, Toku K, Zhang B, Ishihara K, Sakanaka M, Maeda N. Astrocytes prevent neuronal death induced by reactive oxygen and nitrogen species. Glia. 1999;28:85–96
  64. Tindberg N, Ingelman-Sundberg M. Expression, catalytic activity, and inducibility of cytochrome P450 2E1 (CYP2E1) in the rat central nervous system. J Neurochem. 1996;67:2066–2073
  65. Wang XF, Cynader MS. Astrocytes provide cysteine to neurons by releasing glutathione. J Neurochem. 2000;74:1434–1442
  66. Wlodek L, Rommelspacher H. Ethanol-induced changes in the content of thiol compounds and of lipid peroxidation in livers and brains from mice: protection by thiazolidine derivatives. Alcohol Alcohol. 1994;29:649–657
  67. Xu L, Lee JE, Giffard RG. Overexpression of bcl-2, bcl-xL or hsp70 in murine cortical astrocytes reduces injury of co-cultured neurons. Neurosci Lett. 1999;277:193–197
  68. Yanni PA, Rising LJ, Ingraham CA, Lindsley TA. Astrocyte-derived factors modulate the inhibitory effect of ethanol on dendritic development. Glia. 2002;38:292–302
  69. Yoon S-O, Kim M-M, Park S-J, Kim D, Chung J, Chung A-S. Selenite suppresses hydrogen peroxide-induced cell apoptosis through inhibition of ASK1/JNK and activation of PI3K/Akt pathways. FASEB J. 2002;16:111–113

PII: S0741-8329(04)00100-4

doi: 10.1016/j.alcohol.2004.09.001

Alcohol
Volume 33, Issue 2 , Pages 127-138 , June 2004