Alcohol
Volume 34, Issue 2 , Pages 127-132 , October 2004

Effect of ethanol on 24-hour hormonal changes in peripubertal male rats

  • Vanessa Jimenez

      Affiliations

    • Departamento de Bioquímica y Biología Molecular III, Facultad de Medicina, Universidad Complutense, Avda Complutense s/n, 28040 Madrid, Spain
  • ,
  • Daniel P. Cardinali

      Affiliations

    • Departamento de Fisiología, Facultad de Medicina, Universidad de Buenos Aires, 1121 Buenos Aires, Argentina
  • ,
  • Pilar Cano

      Affiliations

    • Departamento de Bioquímica y Biología Molecular III, Facultad de Medicina, Universidad Complutense, Avda Complutense s/n, 28040 Madrid, Spain
  • ,
  • María P. Alvarez

      Affiliations

    • Biología Celular, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain
  • ,
  • Carlos F. Reyes Toso

      Affiliations

    • Departamento de Fisiología, Facultad de Medicina, Universidad de Buenos Aires, 1121 Buenos Aires, Argentina
  • ,
  • Ana I. Esquifino

      Affiliations

    • Departamento de Bioquímica y Biología Molecular III, Facultad de Medicina, Universidad Complutense, Avda Complutense s/n, 28040 Madrid, Spain
    • Corresponding Author InformationCorresponding author. Tel.: +34913941678; fax: +34913941691.

Received 8 March 2004 ,Revised 21 June 2004 ,Accepted 29 June 2004.

References 

  1. Adams ML, Nock B, Truong R, Cicero TJ. Nitric oxide control of steroidogenesis: endocrine effects of NG-nitro-l-arginine and comparisons to alcohol. Life Sci. 1992;50:PL35–PL40
  2. Calogero AE, Burrello N, Ossino AM, Weber RFA, D'Agata R. Interaction between prolactin and catecholamines on hypothalamic GnRH release in vitro. J Endocrinol. 1996;151:269–275
  3. Cardinali DP, Golombek DA. The rhythmic GABAergic system. Neurochem Res. 1998;23:607–614
  4. Castrillón PO, Cardinali DP, Pazo D, Cutrera RA, Esquifino AI. Effect of superior cervical ganglionectomy on 24-h variations in hormone secretion from the anterior hypophysis and in hypothalamic monoamine turnover during the preclinical phase of Freund's adjuvant arthritis in rats. J Neuroendocrinol. 2001;13:288–295
  5. Cicero TJ. Alcohol-induced deficits in the hypothalamic–pituitary–luteinizing hormone axis in the male. Alcohol Clin Exp Res. 1982;6:207–215
  6. Danel T, Touitou Y. Alcohol decreases the nocturnal peak of TSH in healthy volunteers. Psychopharmacology (Berl). 2003;170:213–214
  7. Dodd H, Shorey-Kutschke RL. Ethanol lowers heart carnitine in the methionine and choline deficient rat. Alcohol. 1987;4:395–399
  8. Emanuele MA, Emanuele N. Alcohol and the male reproductive system. Alcohol Res Health. 2001;25:282–287
  9. Emanuele MA, LaPaglia N, Steiner J, Jabamoni K, Hansen M, Kirsteins L, et al. Reversal of ethanol-induced testosterone suppression in peripubertal male rats by opiate blockade. Alcohol Clin Exp Res. 1998;22:1199–1204
  10. Emanuele MA, Metcalfe L, Soneru I, Reda D, Kirsteins L, Emanuele NV, et al. The effect of ethanol on prolactin release from pituitary cells in vitro. Alcohol. 1987;4:429–432
  11. Emanuele NV, Lapaglia N, Emanuele MA. Impact of acute and chronic ethanol exposure on prolactin in both male and female rats. Endocrine. 2001;16:29–37
  12. Esquifino AI, Chacón F, Jimenez V, Reyes Toso CF, Cardinali DP. 24-hour changes in circulating prolactin, follicle-stimulating hormone, luteinizing hormone and testosterone in male rats subjected to social isolation. J Circadian Rhythms. 2004;2:1–6
  13. Esquifino AI, Mateos A, Agrasal C, Martin I, Canovas JM, Fermoso J. Time-dependent effects of alcohol on the hypothalamic–hypophyseal–testicular function in the rat. Alcohol Clin Exp Res. 1989;13:219–223
  14. Fermoso J, Esquifino AI, Mateos A, Agrasal C, Martin I. Possible role of prolactin in the induction of hypogonadism by chronic alcohol treatment in the male rat. Pharmacol Biochem Behav. 1988;29:489–493
  15. Garbutt JC, Miller LP, Mundle L, Senger M, Mason GA. Thyrotropin and prolactin responses to thyrotropin-releasing hormone in young men at high or low risk for alcoholism. Alcohol Clin Exp Res. 1995;19:1133–1140
  16. García-Bonacho M, Esquifino AI, Castrillón PO, Reyes Toso C, Cardinali DP. Age-dependent effect of Freund's adjuvant on 24-hour rhythms in plasma prolactin, growth hormone, thyrotropin, insulin, follicle-stimulating hormone, luteinizing hormone and testosterone in rats. Life Sci. 2000;66:1969–1977
  17. Hastings MH, Reddy AB, Maywood ES. A clockwork web: circadian timing in brain and periphery, in health and disease. Nat Rev Neurosci. 2003;4:649–661
  18. Institute of Laboratory Animal Resources , Commission on Life Sciences , National Research Council . Guide for the Care and Use of Laboratory Animals. Washington, DC: National Academy Press; 1996;
  19. Kim JH, Kim HJ, Noh HS, Roh GS, Kang SS, Cho GJ, et al. Suppression by ethanol of male reproductive activity. Brain Res. 2003;989:91–98
  20. Lieber CS, DeCarli LM. Animal models of chronic ethanol toxicity. Methods Enzymol. 1994;233:585–594
  21. Little PJ, Adams ML, Cicero TJ. Effects of alcohol on the hypothalamic–pituitary–gonadal axis in the developing male rat. J Pharmacol Exp Ther. 1992;263:1056–1061
  22. Mannisto PT, Vedernikova NN, Borisenko SA, Tuominen RK, Kiianmaa K, Burov YV. Effect of chronic ethanol administration and abstinence on serum thyroid-stimulating hormone, prolactin and growth hormone concentrations in rats with high and low ethanol intake. Alcohol Alcohol. 1987;22:251–256
  23. Martí O, Gavaldà A, Jolín T, Armario A. Effect of regularity of exposure to chronic immobilization stress on the circadian pattern of pituitary adrenal hormones, growth hormone, and thyroid stimulating hormone in the adult male rat. Psychoneuroendocrinology. 1993;18:67–77
  24. Mistlberger RE. Circadian food-anticipatory activity: formal models and physiological mechanisms. Neurosci Biobehav Rev. 1994;18:171–195
  25. Moore-Ede MC. Physiology of the circadian system: predictive versus reactive homeostasis. Am J Physiol. 1986;250(5 Pt 2):R737–R752
  26. Rivier C. Alcohol rapidly lowers plasma testosterone levels in the rat: evidence that a neural brain–gonadal pathway may be important for decreased testicular responsiveness to gonadotropin. Alcohol Clin Exp Res. 1999;23:38–45
  27. Rosenwasser AM. Alcohol, antidepressants, and circadian rhythms. Human and animal models. Alcohol Res Health. 2001;25:126–135
  28. Salonen I, Pakarinen P, Huhtaniemi I. Effect of chronic ethanol diet on expression of gonadotropin genes in the male rat. J Pharmacol Exp Ther. 1992;260:463–467
  29. Samochowiec J, Kleinrok Z, Jagiello-Wojtowicz E, Horodnicki J, Rommelspacher H, Schmidt LG. Effects of dopaminergic agonists and antagonists on the serum prolactin levels in alcoholized rats. Pol J Pharmacol. 1997;49:221–227
  30. Sato F, Nakamura K, Taguchi M, Aoki H, Aoki T, Yasuda N. Studies on the site of ethanol action in inducing prolactin release in male rats. Metabolism. 1996;45:1330–1334
  31. Seilicovich A, Duvilanski BH, Gimeno M, Franchi AM, del Carmen Diaz M, Lasaga M. Possible mechanisms of action of ethanol-induced release of prolactin from rat anterior pituitary. J Pharmacol Exp Ther. 1988;246:1123–1128
  32. Shi Q, Hales DB, Emanuele NV, Emanuele MA. Interaction of ethanol and nitric oxide in the hypothalamic–pituitary–gonadal axis in the male rat. Alcohol Clin Exp Res. 1998;22:1754–1762
  33. Srikanth V, Balasubramanian K, Govindarajulu P. Effects of ethanol treatment on Leydig cellular NADPH-generating enzymes and lipid profiles. Endocr J. 1995;42:705–712

PII: S0741-8329(04)00163-6

doi: 10.1016/j.alcohol.2004.06.010

Alcohol
Volume 34, Issue 2 , Pages 127-132 , October 2004