Alcohol
Volume 36, Issue 1 , Pages 1-3 , May 2005

Tryptophan hydroxylase polymorphism is associated with age of onset of alcoholism related behaviors

  • In-Won Chung

      Affiliations

    • Department of Neuropsychiatry, Dongguk University International Hospital, Gyeonggi, Republic of Korea
    • Department of Psychiatry, Dongguk University College of Medicine, Gyeongbuk, Republic of Korea
    • Corresponding Author InformationCorresponding author. Tel.: +82-31-961-7231; fax: +82-31-961-7089.
    • ,
  • Heon Kim

      Affiliations

    • Department of Preventive Medicine, College of Medicine, Chungbuk National University, Chungbuk, Republic of Korea
    • ,
  • William Sribney

      Affiliations

    • Behavioral and Research Training Institute, University Behavioral Healthcare, University of Medicine and Dentistry of New Jersey, Piscataway, NJ, USA
    • ,
  • Joo-Bong Hong

      Affiliations

    • Department of Preventive Medicine, College of Medicine, Chungbuk National University, Chungbuk, Republic of Korea
    • ,
  • Chul-Ho Lee

      Affiliations

    • Department of Preventive Medicine, College of Medicine, Chungbuk National University, Chungbuk, Republic of Korea
    • ,
  • Kyu-Young Lee

      Affiliations

    • Department of Psychiatry and Behavioral Science and Institute of Human Behavioral Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea
    • ,
  • Hong-Mei Nan

      Affiliations

    • Department of Preventive Medicine, College of Medicine, Chungbuk National University, Chungbuk, Republic of Korea
    • ,
  • Yong-Sik Kim

      Affiliations

    • Department of Psychiatry and Behavioral Science and Institute of Human Behavioral Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea
    • ,
  • Paul Manowitz

      Affiliations

    • Department of Psychiatry, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, NJ, USA
    • Tel.: +1-732-235-4347; fax: +1-732-235-4430.

Received 30 March 2005 ,Revised 28 May 2005 ,Accepted 7 June 2005.

References 

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  15. Sigvardsson S, Bohman M, Cloninger CR. Replication of the Stockholm adoption study of alcoholism. Confirmatory cross-fostering analysis. Arch Gen Psychiatry. 1996;53:681–687
  16. Sullivan PF, Jiang Y, Neale MC, Kendler KS, Straub RE. Association of the tryptophan hydroxylase gene with smoking initiation but not progression to nicotine dependence. Am J Med Genet (Neuropsychiatr Genet). 2001;105:479–484
  17. Sun HS, Fann CS-J, Lane H-Y, Chang Y-T, Chang C-J, Liu Y-L, et al. A functional polymorphism in the promoter region of the tryptophan hydroxylase gene is associated with alcohol dependence in one aboriginal group in Taiwan. Alcohol Clin Exp Res. 2005;29:1–7
  18. von Knorring AL, Bohman M, von Knorring L, Oreland L. Platelet MAO activity as a biological marker in subgroups of alcoholism. Acta Psychiatr Scand. 1985;72:51–58

PII: S0741-8329(05)00120-5

doi: 10.1016/j.alcohol.2005.06.004

Alcohol
Volume 36, Issue 1 , Pages 1-3 , May 2005

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