Alcohol
Volume 42, Issue 8 , Pages 683-687 , December 2008

Gastroprotective effect of cyanidin 3-glucoside on ethanol-induced gastric lesions in rats

  • Chun-Ying Li

      Affiliations

    • Department of Biotechnology, School of Life Sciences and Biotechnology, Korea University, Seoul 136-701, South Korea
    • ,
  • Hong-De Xu

      Affiliations

    • Department of Veterinary Medicine, Kangwon National University, Hyoja 2 dong, Chuncheon, Gangwon 200-701, South Korea
    • ,
  • Bing-Tian Zhao

      Affiliations

    • Department of Biotechnology, Kangwon National University, Hyoja 2 dong, Chuncheon, Gangwon 200-701, South Korea
    • ,
  • Hyo-Ihl Chang

      Affiliations

    • Department of Biotechnology, School of Life Sciences and Biotechnology, Korea University, Seoul 136-701, South Korea
    • ,
  • Hae-Ik Rhee

      Affiliations

    • Department of Biotechnology, Kangwon National University, Hyoja 2 dong, Chuncheon, Gangwon 200-701, South Korea
    • Institute of Bioscience and Biotechnology, Kangwon National University, Hyoja 2 dong, Chuncheon, Gangwon 200-701, South Korea
    • Corresponding Author InformationCorresponding author. Tel.: +82-33-250-6481; fax: +82-33-241-6480.

Received 21 March 2008 ,Revised 31 July 2008 ,Accepted 25 August 2008.

References 

  1. Aebi H. Catalase. Meth. Enzymol. 1984;105:121–126
  2. Arafa HMM, Sayed-Ahmed MM. Protective role of carnitine esters against alcohol-induced gastric lesions in rats. Pharmacol. Res. 2003;48:285–290
  3. Ariyphisi I, Toshiharu A, Sugimura F, Abe M, Matsuo Y, Honda T. Recurrence during maintenance therapy with histamine H2 receptors antagonist in cases of gastric ulcers. The Nihon University J. Med. 1986;28:69–74
  4. Bafna PA, Balaraman R. Anti-ulcer and antioxidant activity of DHC-1, a herbal formulation. J. Ethnopharmacol. 2004;90:123–127
  5. Banerjee S, Hawks C, Miller S, Dahill S, Beattie D, McColl KEI. Effect of Helicobacter pylori and its eradication on gastric juice ascorbic acid. Gut. 1994;35:317–322
  6. Das D, Bandyopadhyay D, Bhattacharjee M, Banerjee RK. Hydroxyl radical is the major causative factor in stress-induced gastric ulceration. Free Radic. Biol. Med. 1997;23:8–18
  7. Das D, Banerjee RK. Effect of stress on antioxidant enzymes and gastric ulceration. Mol. Cell. Biol. 1993;125:115–125
  8. Elliot SN, Wallace JL. Neutrophil-mediated gastrointestinal injury. Can. J. Gastroenterol. 1998;12:559–568
  9. El-Missiry MA, El-Sayed IH, Othman AI. Protection by metal complexes with SOD-mimetic activity against oxidative gastric injury induced by indomethacin and ethanol in rats. Ann. Clin. Biochem. 2001;38:694–700
  10. Halliwell B, Gutteridge JMC. Free Radicals in Biology and Medicine. 3rd ed.. Oxford: Oxford University Press; 2001;pp. 574–680
  11. Hiruma-Lima CA, Gracioso JS, Bighetti EJ, Grassi-Kassisse DM, Nunes DS, Souza Brito AR. Effect of essential oil obtained from Croton cajucara Benth. On gastric ulcer healing and protective factors of the gastric mucosa. Phytomedicine. 2002;9:523–529
  12. Hiruma-Lima CA, Gracioso JS, Toma W, Almeida AB, Paula AC, Brasil DS, et al. Gastroprotective effect of aparisthman, a diterpene isolated from Aparisthmium cordatum on experimental gastric ulcer models in rats and mice. Phytomedicine. 2001;8:94–100
  13. Huh K, Kwon TH, Shin US, Kim WB, Ahn BO, Oh TY, et al. Inhibitory effects of DA-9601 on ethanol-induced gastrohemorrhagic lesions and gastric xanthine oxidase activity in rats. J. Ethnopharmacol. 2003;88:269–273
  14. Kim JH, Choi SK, Choi SY, Kim HK, Chang HI. Suppressive effect of astaxanthin isolated from the Xanthophyllomyces dendrorhous mutant on ethanol-induced gastric mucosal injury in rats. Biosci. Biotechnol. Biochem. 2005;69:1300–1305
  15. Kim JH, Kim SW, Yun CW, Chang HI. Therapeutic effect of Astaxanthin isolated from Xanthophyllomyces dendrorhous mutant against Naproxen-induced gastric antral ulceration in rats. J. Microbiol. Biotechnol. 2005;15:633–639
  16. Konturek PC, Brzowski T, Sliwowski Z, Pajido R, Stachura J, Hahn EG, et al. Involvement of nitric oxide and prostaglandins in gastroprotection induced by bacterial lipopolysaccharide. Scand. J. Gastroenterol. 1998;33:691–700
  17. Lawrence RA, Burk RF. Glutathione peroxidase activity in selenium-deficient rat liver. Biochem. Biophys. Res. Commun. 1976;71:952–958
  18. Mates JM, Perez-Gomez C, Nudez de Castro I. Antioxidant enzymes and human diseases. Clin. Biochem. 1999;32:595–603
  19. Miura T, Muraoka S, Fujimoto Y. Lipid peroxidation induced by indomethacin with horseradish peroxidase and hydrogen peroxide: involvement of indomethacin radicals. Biochem. Pharmacol. 2002;63:2069–2074
  20. Moron MA, Depierrie JW, Mannervik B. Level of glutathione reductase and glutathione S. transferase activities in rat lung and liver. Biochim. Biophys. Acta. 1979;582:67–78
  21. Ohkawa HM, Ohishi W, Yagi K. Assay for lipid peroxides I animal tissues by thiobarbituric acid reaction. Anal. Biochem. 1979;95:351–358
  22. Peskar BM, Maricic N. Role of prostaglandins in gastroprotection. Dig. Dis. Sci. 1998;43:23–29
  23. Rao C, Ramesh KV, Bairy KL, Kulkarni D. Zinc complexes and NSAID abolish gastric ulceration propensity of parent drugs. Indian Drugs. 1990;28:64
  24. Ray A, Henke PG, Sullivan RM. Noradrenogenic mechanisms in the central amygdalar nucleus and gastric stress ulcer formation in rats. Neuroscience. 1990;110:331–336
  25. Rethinam SD, Shoba N, Ganapathy V, Chennam SSD. Gastroprotective effect of Terminalia arjuna bark on diclofenac sodium induced gastric ulcer. Chem. Biol. Interact. 2007;13
  26. Romilda C, Antonia D, Michelangelo F, Attilio C, Remo N, Fabio F. Hepatocyte proliferation and apoptosis in relation to oxidative damage in alcohol-related liver disease. Alcohol Alcohol. 2002;37:43–48
  27. Shaw S, Herbert V, Colman N, Jayatilleke E. Effect of ethanol-generated free radicals on gastric intrinsic factor and glutathione. Alcohol. 1990;7:153–157
  28. Sheeba MS, Asha VV. Effect of Cardiospermum halicacabum on ethanol-induced gastric ulcers in rats. J. Ethnopharmacol. 2006;106:105–110
  29. Sun Y, Larry WO, Ying L. A simple method for clinical assay of superoxide dismutase. Clin. Chem. 1988;34:497–500
  30. Tsuda T, Watanabe M, Ohshima K, Norinobu S, Choi SW, Kawakishi S, et al. Antioxidative activity of the anthocyanin pigments cyanidin 3-O-β-D-glucoside and cyanidin. J. Agric. Food Chem. 1994;42:2407–2410
  31. Umamaheswari M, Asokkumar K, Rathidevi R, Sivashanmugam AT, Subhadradevi V, Ravi TK. Antiulcer and in vitro antioxidant activities of Jasminum grandiflorum L.J.. Ethnopharmacology. 2007;110:464–470

PII: S0741-8329(08)00307-8

doi: 10.1016/j.alcohol.2008.08.009

Alcohol
Volume 42, Issue 8 , Pages 683-687 , December 2008

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