« Previous
Next »
Alcohol
Volume 20, Issue 3
, Pages 277-283
, April 2000
Gamma-hydroxybutyric acid as a signaling molecule in brain
References
-
.
Cloning of a rat brain succinic semialdehyde reductase involved in the synthesis of the neuromodulator γ-hydroxybutyrate.
Biochem J. 1998;334:43–50
- . Presynaptic gamma-hydroxybutyric acid (GHB) and gamma-aminobutyric acidB (GABAB) receptor-mediated release of GABA and glutamate (GLU) in rat thalamic ventrobasal nucleus (VB) (a possible mechanism for the generation of absence-like seizures induced by GHB). J Pharmacol Exp Ther. 1995;273:1534–1543
- . High affinity binding site for γ-hydroxybutyric acid in rat brain. Life Sci. 1982;30:953–961
-
.
Experimental absence seizures (potential role of γ-hydroxybutyric acid and GABABreceptors).
J Neural Transm. 1992;35:155–177
- . Purification from human brain and some properties of two NADPH-linked aldehyde reductases which reduce succinic semialdehyde to 4-hydroxybutyrate. J Neurochem. 1979;33:1169–1175
- . Low doses of γ-hydroxybutyric acid stimulate the firing rate of dopaminergic neurons in unanesthetized rats. Brain Res. 1991;566:208–211
- . Heterogeneous responses of substantia nigra pars reticulata neurons to γ-hydroxybutyric acid administration. Eur J Pharmacol. 1993;230:363–365
-
.
Gamma-hydroxybutyric acid (GHBA) induces pacemaker activity and inhibition of substantia nigra dopamine neurons by activating GABAB-receptors.
Naunyn-Schmiedebergs Arch Pharmacol. 1993;348:491–497
- . Effect of gamma-hydroxybutyrate and its antagonist NSC-382 on spontaneous cell firing in the prefrontal cortex of the rat. Brain Res. 1995;673:157–160
- . Kinetics of in vivo conversion of γ-[3H]aminobutyric acid to γ-[3H]hydroxybutyric acid by rat brain. J Neurochem. 1977;28:1069–1073
- . The effects of gamma-hydroxybutyrate on the membrane properties of guinea-pig pars compacta neurons in the substantia nigra in vitro. Neuroscience. 1989;31:363–370
- . Effects of phospholipases, proteases and neuraminidase on gamma-hydroxybutyrate binding sites. Mol Cell Biochem. 1990;93:87–94a
- . Trans-gamma-hydroxycrotonic acid binding sites in brain (evidence for a subpopulation of gamma-hydroxybutyrate sites). Neurosci Lett. 1990;110:204–209b
- . Selective distribution pattern of γ-hydroxybutyrate receptors in the rat forebrain and midbrain as revealed by quantitative autoradiography. Brain Res. 1992;572:345–348
- . Gamma-hydroxybutyric acid as hypnotic (clinical and pharmacokinetic evaluation of gamma-hydroxybutyric acid as hypnotic in man). Encephale. 1980;6:93–99
- . γ-Butyrolactone-induced absence-like seizures increase nuclear CRE- and AP-1 DNA-binding activities in mouse brain. Neuropharmacology. 1996;35:45–55
- . γ-Hydroxybutyric acid increases intracellular Ca2+-concentration and nuclear cyclic AMP-responsive element- and activator protein 1 DNA-binding activities through GABAB receptor in cultured cerebellar granule cells. J Neurochem. 1995;65:75–83
- . Neurochemical and electrophysiological evidence for the existence of a functional γ-hydroxybutyrate system in NCB-20 neurons. Neuroscience. 1998;86:989–1000
- . Microiontophoretic study of the mechanism of action of gamma-hydroxybutyric acid. Bull Exp Biol Med. 1980;88:1293–1296
- . Subcellular distribution of γ-hydroxybutyrate binding sites in rat brain (principal localization in the synaptosomal fraction). Biochem Biophys Res Commun. 1983;110:262–265
- . A specific γ-hydroxybutyrate receptor ligand possesses both antagonistic and anticonvulsant properties. J Pharmacol Exp Ther. 1990;255:657–663
- . Displacement of [3H]-hydroxybutyrate binding by benzamide neuroleptics and prochlorperazine but not by other antipsychotics. Eur J Pharmacol. 1994;256:211–214
- . The γ-hydroxybutyrate signalling system in brain (organization and functional implications). Prog Neurobiol. 1997;51:337–361
- . Treatment of narcolepsy with gamma-hydroxybutyrate (a review of clinical and sleep laboratory findings). Sleep. 1986;9:285–289
- . The extraneural distribution of γ-hydroxybutyrate. J Neurochem. 1981;37:1345–1348
- . Inhibition of nigral and neocortical cells by γ-hydroxybutyrate (a microiontophoretic investigation). Eur J Pharmacol. 1979;53:359–364
- . γ-Hydroxybutyrate receptor binding in rat brain is inhibited by guanyl nucleotides and pertussis toxin. Neurosci Lett. 1995;189:51–53
- . Sulpiride, but not haloperidol, up-regulates γ-hydroxybutyrate receptors in vivo and in cultured cells. Eur J Pharmacol. 1998;346:331–337
- . Natural occurrence of gamma-hydroxybutyrate in mammalian brain. Biochem Pharmacol. 1970;19:1087–1093
- . Specific and non-specific succinic semialdehyde reductases from rat brain (isolation and properties). FEBS Lett. 1980;117:111–116
- . Regional and subcellular localization in rat brain of the enzymes that can synthesize γ-hydroxybutyric acid. J Neurochem. 1981;36:1433–1438
- . Ontogeny and distribution of specific succinic semialdehyde reductase apoenzyme in the rat brain. Neurochem Res. 1982;7:555–561
- . Anti-sedative and anti-cataleptic properties of NCS-382, a γ-hydroxybutyrate receptor antagonist. Eur J Pharmacol. 1991;203:393–397
- . The anxiolytic effect of γ-hydroxybutyrate in the elevated plus maze is reversed by the benzodiazepine receptor antagonist, flumazenil. Eur J Pharmacol. 1998;342:21–27
- . γ-Hydroxybutyric acid in subcellular fractions of rat brain. J Neurochem. 1987;48:196–201
- . Evidence for GABAB-mediated mechanisms in experimental generalized absence seizures. Eur J Pharmacol. 1992;213:343–349
- . The ontogeny of [3H]γ-hydroxybutyrate and [3H]GABAB binding sites (relation to the development of experimental absence seizures). Brain Res. 1994;659:147–156
- . GABAA receptor function in the γ-hydroxybutyrate model of generalized absence seizures. Neuropharmacology. 1993;32:401–409
- . γ-Hydroxybutyric acid binding sites (interaction with the GABA-benzodiazepine-picrotoxin receptor complex). Neurochem Res. 1992;17:201–204
- . γ-Hydroxybutyrate stimulation of the formation of cyclic GMP and inositol phosphates in rat hippocampal slices. J Neurochem. 1989;52:1382–1387
- . 3′-5′ Cyclic-guanosine monophosphate increase in rat brain hippocampus after gamma-hydroxybutyrate administration (prevention by valproate and naloxone). Life Sci. 1987;41:605–610
- . Gamma-hydroxybutyrate promotes oscillatory activity of rat and cat thalamocortical neurons by a tonic GABAB receptor-mediated hyperpolarization. Neuroscience. 1995;66:133–141
- . Gamma-hydroxybutyrate depresses monosynaptic excitatory and inhibitory postsynaptic potentials in rat hippocampal slices. Eur J Pharmacol. 1992;223:193–196
PII: S0741-8329(99)00092-0
© 2000 Elsevier Science Inc. All rights reserved.
« Previous
Next »
Alcohol
Volume 20, Issue 3
, Pages 277-283
, April 2000
