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Biotransformation of ethanol to ethyl glucuronide in a rat model after a single high oral dosage
24 October 2011
Trista H. Wright, Kenneth E. Ferslew
Abstract: Ethyl glucuronide (EtG) is a minor ethanol metabolite that confirms the absorption and metabolism of ethanol after oral or dermal exposure. Human data suggest that maximum blood EtG (BEtG) c...
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Baseline trajectories of heavy drinking and their effects on postrandomization drinking in the COMBINE Study: empirically derived predictors of drinking outcomes during treatment
19 September 2011
Ralitza Gueorguieva, Ran Wu, Dennis Donovan, Bruce James Rounsaville, David Couper, John Harrison Krystal, Stephanie Samples O’Malley
Abstract: The Combined Pharmacotherapies and Behavioral Interventions (COMBINE) Study sought to answer questions about the benefits of combining behavioral and pharmacological interventions (naltrexon...
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Alcohol and inflammation and infection: clinical and experimental systems—summary of the 2010 Alcohol and Immunology Research Interest Group Meeting
15 September 2011
Anita Zahs, Robert T. Cook, Thomas J. Waldschimdt, Mashkoor A. Choudhry, Elizabeth J. Kovacs, Melanie D. Bird
Abstract: The 15th annual meeting of the Alcohol and Immunology Research Interest Group was held on November 19, 2010, at Loyola University Medical Center in Maywood, IL. This year, the focus of the m...
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The decrease of serum MMP-2 activity corresponds to alcoholic cirrhosis stage
12 September 2011
Agnieszka Madro, Grazyna Czechowska, Maria Slomka, Krzysztof Celinski, Stanislawa Szymonik-Lesiuk, Jacek Kurzepa
Abstract: Because of numerous limitations for liver biopsy, a noninvasive marker of liver cirrhosis is sought. Promising indicators seem to be matrix metalloproteinases (MMPs) that are responsible for...
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Association of alcohol, alcohol and tobacco with mortality: findings from a prospective cohort study in Mumbai (Bombay), India
12 September 2011
Mangesh S. Pednekar, Genevieve Sansone, Prakash C. Gupta
Abstract: The aim of the present study was to examine the association between alcohol, alcohol and tobacco, and mortality in a large adult population in the city of Mumbai. A total of 35,102 men aged ...
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