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Young investigators stress alcohol-induced neuroadaptations in extended amygdala
22 March 2012
Excessive alcohol use, alcohol abuse, and relapse to heavy drinking are all characteristic of alcohol use disorders. Brain circuits controlling reward, appetitive behavior, decision making and habit f...
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David M. Lovinger
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299-300
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Introduction to Young Investigator Award Symposium: Symposium XII: Young Investigator Award
30 April 2012
The growing health burdens of alcohol addiction and stress-related disorders demand novel treatment strategies and new advances in biomedical research. Alcoholism and Stress: A Framework for Future Tr...
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Marisa Roberto,
Thomas L. Kash,
Patrick J. Mulholland,
Vincent N. Marty,
Nicholas W. Gilpin,
Brendan M. Walker
et al.
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301-302
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The role of biogenic amine signaling in the bed nucleus of the stria terminals in alcohol abuse
27 March 2012
Abstract: There is a growing body of evidence that suggests that stress and anxiety can influence the development of alcohol use disorders. This influence is believed to be due in part to persistent a...
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Thomas Louis Kash
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303-308
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KCa2 channels: Novel therapeutic targets for treating alcohol withdrawal and escalation of alcohol consumption
05 April 2012
Abstract: Small-conductance, calcium-activated potassium (KCa2) channels influence neuronal firing properties, intrinsic excitability, and NMDA receptor-dependent synaptic responses and plasticity. In...
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Patrick J. Mulholland
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309-315
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Effects of alcohol on the membrane excitability and synaptic transmission of medium spiny neurons in the nucleus accumbens
26 March 2012
Abstract: Chronic and excessive alcohol drinking lead to alcohol dependence and loss of control over alcohol consumption, with serious detrimental health consequences. Chronic alcohol exposure followe...
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Vincent N. Marty,
Igor Spigelman
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317-327
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Corticotropin-releasing factor (CRF) and neuropeptide Y (NPY): Effects on inhibitory transmission in central amygdala, and anxiety- & alcohol-related behaviors
07 May 2012
Abstract: The central amygdala (CeA) is uniquely situated to function as an interface between stress- and addiction-related processes. This brain region has long been attributed an important role in a...
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Nicholas W. Gilpin
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329-337
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Conceptualizing withdrawal-induced escalation of alcohol self-administration as a learned, plasticity-dependent process
30 March 2012
Abstract: This article represents one of five contributions focusing on the topic “Plasticity and neuroadaptive responses within the extended amygdala in response to chronic or excessive alcohol expos...
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Brendan M. Walker
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339-348
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Urocortins: CRF's siblings and their potential role in anxiety, depression and alcohol drinking behavior
23 March 2012
Abstract: It is widely accepted that stress, anxiety, depression and alcohol abuse-related disorders are in large part controlled by corticotropin-releasing factor (CRF) receptors. However, evidence i...
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Andrey E. Ryabinin,
Michael M. Tsoory,
Tamas Kozicz,
Todd E. Thiele,
Adi Neufeld-Cohen,
Alon Chen,
Emily G. Lowery-Gionta,
William J. Giardino,
Simranjit Kaur
et al.
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349-357
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Targeting dynorphin/kappa opioid receptor systems to treat alcohol abuse and dependence
29 March 2012
Abstract: This review represents the focus of a symposium that was presented at the “Alcoholism and Stress: A Framework for Future Treatment Strategies” conference in Volterra, Italy on May 3–6, 2011 ...
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Brendan M. Walker,
Glenn R. Valdez,
Jay P. McLaughlin,
Georgy Bakalkin
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359-370
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Effects of early life stress on drinking and serotonin system activity in rhesus macaques: 5-hydroxyindoleacetic acid in cerebrospinal fluid predicts brain tissue levels
26 March 2012
Abstract: Early childhood stress is a risk factor for the development of substance-abuse disorders. A nonhuman primate model of early life stress, social impoverishment through nursery-rearing rather ...
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Kimberly N. Huggins,
Tiffany A. Mathews,
Jason L. Locke,
Kendall T. Szeliga,
David P. Friedman,
Allyson J. Bennett,
Sara R. Jones
et al.
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371-376
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Ethanol up-regulates nucleus accumbens neuronal activity dependent pentraxin (Narp): Implications for alcohol-induced behavioral plasticity
23 March 2012
Abstract: Neuronal activity dependent pentraxin (Narp) interacts with α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) glutamate receptors to facilitate excitatory synapse formation by aggreg...
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Alexis W. Ary,
Debra K. Cozzoli,
Deborah A. Finn,
John C. Crabbe,
Marlin H. Dehoff,
Paul F. Worley,
Karen K. Szumlinski
et al.
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377-387
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Timing-dependent reduction in ethanol sedation and drinking preference by NMDA receptor co-agonist d-serine
26 March 2012
Abstract: NMDA receptors become a major contributor to acute ethanol intoxication effects at high concentrations as ethanol binds to a unique site on the receptor and inhibits glutamatergic activity i...
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Amber Lockridge,
Gabriel Romero,
Justin Harrington,
Brett Newland,
Zi Gong,
Andrew Cameron,
Li-Lian Yuan
et al.
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389-400
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